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  V1756    AKSci Reference Standard
Glabridin
, 99% (HPLC)
 
4-(3,4-Dihydro-8,8-dimethyl-2H,8H-benzo(1,2-b:3,4-b'')dipyran-3-yl)-1,3-benzenediol




IDENTITY
CAS Number:59870-68-7
MDL Number:MFCD03427694
MF:C20H20O4
MW:324.37
SPECIFICATIONS & PROPERTIES
Min. Purity Spec:99% (HPLC)
Physical Form (at 20°C):Solid
Melting Point:227-230°C
Optical Rotation:+7.0° (c=0.5, DMSO)
Long-Term Storage:Store long-term at -20°C
DOT/IATA TRANSPORT INFORMATION
Not hazardous material

BIOLOGICAL INFO
Solubility:DMSO: =14 mg/mL

REVIEW

 Glabridin is a bio-available isoflavan isolated from licorice (Glycyrrhiza glabra L.) root extract. Glabridin has been reported to posses varies biological activities including strong antioxidant activity, antioxidant against LDL oxidation, anti-Helicobacter pylori properties, estrogen-like activity and antinephritic and radical scavenging activities. Also it appears to inhibit serotonin re-uptake, melanogenesis, inflammation and cytochrome P450 3A4, 2B6, and 2C9.

REFERENCES
[1]Jirawattanapong, Warunee; Archives of Pharmacal Research 2009, V32(5), P647-654

GLOBALLY HARMONIZED SYSTEM (GHS)

Pictograms

Signal Word
None

Hazard Statements
H413

Precautionary Statements
P273; P501


Current as of February 3, 2025

AKSci Reference Standards are high-purity, low-impurity compounds suitable for use as standards.


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CATEGORIES

 APIs and Bioactives > Natural Products


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