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  J10388    AKSci Reference Standard
Betamethasone dipropionate, >98% (HPLC)
 
9alpha-Fluoro-16beta-methyl-11beta,17alpha,21-trihydroxy-1,4-pregnadiene-3,20-dione 17,21-dipropionate
Betamethasone Dipropionate
Diprolene
IDENTITY
CAS Number:5593-20-4
MDL Number:MFCD00072035
MF:C28H37FO7
MW:504.59
EINECS:227-005-2
SPECIFICATIONS & PROPERTIES
Min. Purity Spec:>98% (HPLC)
Physical Form (at 20°C):Solid
Melting Point:170-179°C
Optical Rotation:+66.0-+72.0° (c=1, Dioxane)
Long-Term Storage:Store long-term in a cool, dry place
DOT/IATA TRANSPORT INFORMATION
Not hazardous material

BIOLOGICAL INFO
Solubility:DMSO: 100mg/mL; H2O: <1mg/mL; EtOH: 66mg/mL
Application(s):Anti-Inflammatory Agent
Form:Free Base

REVIEW
 A glucocorticoid steroid with anti-inflammatory and immunosuppressive abilities.

REFERENCES
[1]McCormack PL (2011). Spotlight on calcipotriene/betamethasone dipropionate in psoriasis vulgaris of the trunk, limbs, and scalp. Am J Clin Dermatol. 12(6):421-4. PMID 21967117.
[2] Patel T, Bhutani T, Busse KL, Koo J (2011). Evaluating the efficacy and safety of calcipotriene/betamethasone ointment occluded with a hydrogel patch: a 6-week bilaterally controlled, investigator-blinded trial. Cutis. 88(3):149-54. PMID 22017069.

GLOBALLY HARMONIZED SYSTEM (GHS)

Pictograms

Signal Word
Warning

Hazard Statements
H315; H319; H335

Precautionary Statements
P261; P264; P271; P280; P302+P352; P304+P340; P305+P351+P338; P312; P321; P332+P313; P337+P313; P362; P403+P233; P405; P501

Current as of May 21, 2025

AKSci Reference Standards are high-purity, low-impurity compounds suitable for use as standards.


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CATEGORIES
 APIs and Bioactives > Steroid Hormones


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