REVIEW Imidocarb dispropionate is a symmetrical urea salt used as an antiprotozoal agent for infection with Babesia and other parasites of cattle, sheep, horses and dogs. The mode of action is uncertain, though two mechanisms have been proposed: interference with production or utilization of polyamines, and prevention of entry of inositol into the erythrocytes containing the parasites.
REFERENCES
[1]
Kuttler, KL (1980). Pharmacotherapeutics of drugs used in treatment of anaplasmosis and babesiosis. Journal of the American Veterinary Medical Association 176 (10 Spec No): 1103-8. PMID 7216881.
[2]
Joyner LP The chemotherapy of protozoal infections of veterinary importance. J Protozool. 1981 Feb;28(1):17-9.
[3]
MacNeil, J. D. Imidocarb dipropionate FAO Food and Nutrition Paper (1999), 41(11, Residues of Some Veterinary Drugs in Animals and Foods), 65-77.
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Vial HJ, Gorenflot A.Chemotherapy against babesiosis.Vet Parasitol. 2006 May 31;138(1-2):147-60.
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