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  S601    AKSci Bulk Reagent
Bergenin
, 98% (HPLC)
 
Cuscutin




IDENTITY
CAS Number:477-90-7
MDL Number:MFCD00133120
MF:C14H16O9
MW:328.27
SPECIFICATIONS & PROPERTIES
Min. Purity Spec:98% (HPLC)
Physical Form (at 20°C):Solid
Melting Point:242-245°C
Optical Rotation:-37.0 to -40.0°, (c=2, MeOH)
Long-Term Storage:Store long-term at -20°C
DOT/IATA TRANSPORT INFORMATION
Not hazardous material

BIOLOGICAL INFO
Application(s):Cancer
Form:Free Base
Research Area:Immunology

REVIEW

 Bergenin, also called cuscutin, is a natural product iolated from Bergenia species like Bergenia ciliata and Bergenia ligulata, from rhizomes of Bergenia stracheyi. It is also found in the stem bark of Dryobalanops aromatica, in Ardisia elliptica and in Mallotus japonicus. Bergenin is the C-glycoside of 4-O-methyl gallic acid. These are chemical compounds and drugs of Ayurveda, a system of traditional medicine native to the Indian subcontinent and a form of alternative medicine. Bergenin shows wide ranging pharmacological activities; immunomodulation, antihepatotoxic, antiarrhythmic and antiparasitic properties.

REFERENCES
[1]Kim HS, Lim HK, Chung MW, Kim YC. Antihepatotoxic activity of bergenin, the major constituent of Mallotus japonicus, on carbon tetrachloride-intoxicated hepatocytes. J Ethnopharmacol. 2000 Jan;69(1):79-83.
[2] Pu HL, Huang X, Zhao JH, Hong A;. Bergenin is the antiarrhythmic principle of Fluggea virosa. Planta Med. 2002 Apr;68(4):372-4.
[3] Nazir N, Koul S, Qurishi MA, Taneja SC, Ahmad SF, Bani S, Qazi GN. Immunomodulatory effect of bergenin and norbergenin against adjuvant-induced arthritis--a flow cytometric study. J Ethnopharmacol. 2007 Jun 13;112(2):401-5.
[4] Kobayashi H, de Mejía E. The genus Ardisia: a novel source of health-promoting compounds and phytopharmaceuticals, J Ethnopharmacol. 2005 Jan 15;96(3):347-54.

GLOBALLY HARMONIZED SYSTEM (GHS)

Pictograms

Signal Word
Warning

Hazard Statements
H315; H319; H335

Precautionary Statements
P261; P264; P271; P280; P302+P352; P304+P340; P305+P351+P338; P312; P321; P332+P313; P337+P313; P362; P403+P233; P405; P501


Current as of December 23, 2024


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All batches backed with full quality assurance.
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All products are for research and development use only, not for any other uses, and must be handled by technically-qualified persons.

These products are explicitly not intended to be used in foods and/or cosmetics and/or drugs (human and veterinary) and/or consumer products and/or biocides and/or pesticides of any kind unless explicitly stated otherwise.

Products are not sold to individuals. We do not ship to residential addresses. Consumer orders will be cancelled without notice.

New customers undergo an internal onboarding process. As part of this process, new customers may be asked for more information. Additional restrictions may apply.



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