REVIEW Imidocarb is a symmetrical urea used as an antiprotozoal agent for infection with Babesia and other parasites of cattle, sheep, horses and dogs. The mode of action is uncertain, though two mechanisms have been proposed: interference with production or utilization of polyamines, and prevention of entry of inositol into the erythrocytes containing the parasites.
REFERENCES
[1]
Hashemi-Fesharki R. Studies on imidocarb dihydrochloride in experimental Babesia ovis infection in splenectomized lambs. Br Vet J. 1977 Nov-Dec;133(6):609-14.
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Hashemi-Fesharki R. Studies on imidocarb dihydrochloride in experimental Babesia bigemina infection in calves. Br Vet J. 1975 Nov-Dec;131(6):666-72.
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Kuttler KL. Pharmacotherapeutics of drugs used in treatment of anaplasmosis and babesiosis. J Am Vet Med Assoc. 1980 May 15;176(10 Spec No):1103-8.
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Joyner LP The chemotherapy of protozoal infections of veterinary importance. J Protozool. 1981 Feb;28(1):17-9.
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Vial HJ, Gorenflot A.Chemotherapy against babesiosis.Vet Parasitol. 2006 May 31;138(1-2):147-60.
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