REVIEW Ritodrine HCl is an adrenergic beta2 selective agonist used to control premature labor. It binds to beta-2 adrenergic receptors on outer membrane of myometrial cell, activates adenyl cyclase to increase the level of cAMP which decreases intracellular calcium and leads to a relaxation of uterine smooth muscle and, therefore, a decrease in premature uterine contractions.
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Zanon, Jacopo; Libralon, Giovanna; De Faveri, Carla; Huber, Florian Anton Martin Process for preparation of Ritodrine hydrochloride PCT Int. Appl. (2011), WO 2011134724 A2 20111103.
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