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  J95396    
Triphenyl valsartan
, 95%
 



IDENTITY
CAS Number:195435-23-5
MDL Number:MFCD08460102
MF:C43H43N5O3
MW:677.83
SPECIFICATIONS & PROPERTIES
Min. Purity Spec:95%
Physical Form (at 20°C):Solid
Melting Point:155-161°C
Density:1.2
Refractive Index:1.62
Long-Term Storage:Store long-term in a cool, dry place
DOT/IATA TRANSPORT INFORMATION
Not hazardous material

REVIEW

 Triphenyl valsartan is an advanced intermediate towards the preparation of valsartan, an angiotension II receptor antagonist, used in the treatment of hypertension.

REFERENCES
[1]Buhlmayer, Peter. Preparation of N-aryl amino acid carboxyalkyl ester derivatives as angiotensin II antagonists PCT Int. Appl. (1997), WO 9730036 A1 19970821.
[2] Cordi, Alexis; Haberkorn, Laure; Verbeuren, Tony; Courchay, Christine; Simonet, Serge; New diazenium diolate derivatives, their preparation process, and the pharmaceutical compositions which contain them. Fr. Demande (2007), FR 2902428 A1 20071221.
[3] Preparation of (S)-N-(1-carboxy-2-methyl-prop-1-YL)-N-pentanoyl-N-[2'-(1H-tetrazol-5-yl)biphenyl-4-ylmethyl]amine IP.com Journal (2009), 9(5B), 47.
[4] Dallatomasina, Franco; Guandalini, Luca; Martini, Elisabetta; Romanelli, Maria Novella; Method for deprotecting N-protected tetrazole derivatives Ital. Appl. (2006), IT 2006TO0380 A1 20060825.

GLOBALLY HARMONIZED SYSTEM (GHS)

Pictograms

Signal Word
Warning

Hazard Statements
H315; H319; H335

Precautionary Statements
P261; P264; P271; P280; P302+P352; P304+P340; P305+P351+P338; P312; P321; P332+P313; P337+P313; P362; P403+P233; P405; P501


Current as of January 6, 2025


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All products are stocked and shipped from the SF Bay, California, USA via FedEx, UPS or DHL.
All batches backed with full quality assurance.
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All products are for research and development use only, not for any other uses, and must be handled by technically-qualified persons.

These products are explicitly not intended to be used in foods and/or cosmetics and/or drugs (human and veterinary) and/or consumer products and/or biocides and/or pesticides of any kind unless explicitly stated otherwise.

Products are not sold to individuals. We do not ship to residential addresses. Consumer orders will be cancelled without notice.

New customers undergo an internal onboarding process. As part of this process, new customers may be asked for more information. Additional restrictions may apply.



CATEGORIES

 APIs and Bioactives > Angiotensin Receptor Blockers


PubChem
  @PubMed
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