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  J11237    
Benzarone
, 99% (HPLC), powder
 
(2-Ethylbenzofuran-3-yl)(4-hydroxyphenyl)methanone, NSC 82134




IDENTITY
CAS Number:1477-19-6
MDL Number:MFCD00867417
MF:C17H14O3
MW:266.29
SPECIFICATIONS & PROPERTIES
Min. Purity Spec:99% (HPLC), powder
Physical Form (at 20°C):Solid
Melting Point:124-128°C
Long-Term Storage:Store long-term in a cool, dry place
DOT/IATA TRANSPORT INFORMATION
Not hazardous material

BIOLOGICAL INFO
Application(s):Uric Acid Transporter 1 (hURAT1) and human fatty acid binding protein 4

REVIEW

 Benzarone is a thrombolytic drug used as a vasoprotective agent.Initially used for the treatment of gout and now used in antivaricose therapy. Benzarone has been recently shown to be an inhibitor of Uric Acid Transporter 1 (hURAT1) and human fatty acid binding protein 4.

REFERENCES
[1]Marmo, Emilio. Pharmacodynamic characteristics of benzarone, 2-ethyl-(p-hydroxybenzoyl)benzofuran, Archivio Italiano di Scienze Farmacologiche (1965), 15(1-2), 73-5.
[2] Chaillet, Francois; Barchewitz, G.; Charlier, Robert; Guilbert, A.; Colot, M.; Deltour, G. Benzofurans. XLIII. Angiotropic, antiinflammatory, and fibrinolytic properties of benzarone Arzneimittel-Forschung (1970), 20(3), 358-63.
[3] Chaillet, F.; Barchewitz, G.; Charlier, R.; Guilbert, A.; Colot, M.; Deltour, G. Angiotrophic, antiinflammatory, and fibrinolytic properties of benzarone Gazzetta Medica Italiana (1971), 130(2), 75-85.
[4] Brotelle, R. The antithrombotic properties of Fragivix Ergebnisse der Angiologie (1976), 11, 83-95.

GLOBALLY HARMONIZED SYSTEM (GHS)

Pictograms

Signal Word
Warning

Hazard Statements
H302; H413

Precautionary Statements
P264; P270; P273; P301+P312; P330; P501


Current as of January 5, 2025


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All products are stocked and shipped from the SF Bay, California, USA via FedEx, UPS or DHL.
All batches backed with full quality assurance.
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All products are for research and development use only, not for any other uses, and must be handled by technically-qualified persons.

These products are explicitly not intended to be used in foods and/or cosmetics and/or drugs (human and veterinary) and/or consumer products and/or biocides and/or pesticides of any kind unless explicitly stated otherwise.

Products are not sold to individuals. We do not ship to residential addresses. Consumer orders will be cancelled without notice.

New customers undergo an internal onboarding process. As part of this process, new customers may be asked for more information. Additional restrictions may apply.



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