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  E047    
Rizatriptan benzoate
, 98% (HPLC), powder
 
MK-462
Maxalt
N,N-Dimethyl-2-[5-(1,2,4-triazol-1-ylmethyl)-1H-indol-3-yl]ethylamine benzoate salt




IDENTITY
CAS Number:145202-66-0
MDL Number:MFCD00866224
MF:C22H25N5O2
MW:391.47
SPECIFICATIONS & PROPERTIES
Min. Purity Spec:98% (HPLC), powder
Physical Form (at 20°C):Solid
Melting Point:175-184°C
Long-Term Storage:Store long-term in a cool, dry place
DOT/IATA TRANSPORT INFORMATION
Not hazardous material

BIOLOGICAL INFO
Solubility:DMSO: 20mg/mL; H2O: 46mg/mL; EtOH: <1mg/mL
Application(s):5-HT1 agonist
Form:Benzoate salt

REVIEW

 A serotonin 5-HT1 agonist triptan drug for the treatment of migraine headaches.

REFERENCES
[1]Ho TW, Pearlman E, Lewis D, H?m?l?inen M, Connor K, Michelson D, Zhang Y, Assaid C, Mozley LH, Strickler N, Bachman R, Mahoney E, Lines C, Hewitt DJ; Rizatriptan Protocol 082 Pediatric Migraine Study Group (2012). Efficacy and tolerability of rizatriptan in pediatric migraineurs: results from a randomized, double-blind, placebo-controlled trial using a novel adaptive enrichment design. Cephalalgia. 32(10):750-65. PMID 22711898.
[2] Müller T, Lohse L (2011). Efficacy of parecoxib, sumatriptan, and rizatriptan in the treatment of acute migraine attacks. Clin Neuropharmacol. 34(6):206-9. PMID 21996647.

GLOBALLY HARMONIZED SYSTEM (GHS)

Pictograms

Signal Word
Danger

Hazard Statements
H360

Precautionary Statements
P201; P202; P281; P308+P313; P405; P501


Current as of December 23, 2024


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All products are stocked and shipped from the SF Bay, California, USA via FedEx, UPS or DHL.
All batches backed with full quality assurance.
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All products are for research and development use only, not for any other uses, and must be handled by technically-qualified persons.

These products are explicitly not intended to be used in foods and/or cosmetics and/or drugs (human and veterinary) and/or consumer products and/or biocides and/or pesticides of any kind unless explicitly stated otherwise.

Products are not sold to individuals. We do not ship to residential addresses. Consumer orders will be cancelled without notice.

New customers undergo an internal onboarding process. As part of this process, new customers may be asked for more information. Additional restrictions may apply.



CATEGORIES

 APIs and Bioactives > Serotonin Agonists


PubChem
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