REVIEW Triphenyl irbesartan is an advanced intermediate used in the preparation of irbesartan, an angiotension II antagonist, used in the treatment of hypertension.
REFERENCES
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Bernhart, Claude; Breliere, Jean Claude; Clement, Jacques; Nisato, Dino; Perreaut, Pierre; Preparation of N-(carboxybiphenylylmethyl)spiro[cycloalkane-imidazolinone] derivatives and analogs as angiotensin II inhibitors. PCT Int. Appl. (1991), WO 9114679 A1 19911003.
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Spinale, Francis Guy; N-substituted spirocyclopentaneimidazolinone derivatives for the treatment or prevention of cardiac arrhythmia. Can. Pat. Appl. (1996), CA 2154807 A1 19960223.
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