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  I998    AKSci Bulk Reagent
Triphenyl irbesartan
, 98%
 



IDENTITY
CAS Number:138402-10-5
MDL Number:MFCD08460099
MF:C44H42N6O
MW:670.84
SPECIFICATIONS & PROPERTIES
Min. Purity Spec:98%
Physical Form (at 20°C):Solid
Melting Point:142-148°C
Density:12
Refractive Index:1.66
Long-Term Storage:Store long-term at -20°C
DOT/IATA TRANSPORT INFORMATION
Not hazardous material

REVIEW

 Triphenyl irbesartan is an advanced intermediate used in the preparation of irbesartan, an angiotension II antagonist, used in the treatment of hypertension.

REFERENCES
[1]Bernhart, Claude; Breliere, Jean Claude; Clement, Jacques; Nisato, Dino; Perreaut, Pierre; Preparation of N-(carboxybiphenylylmethyl)spiro[cycloalkane-imidazolinone] derivatives and analogs as angiotensin II inhibitors. PCT Int. Appl. (1991), WO 9114679 A1 19911003.
[2] Spinale, Francis Guy; N-substituted spirocyclopentaneimidazolinone derivatives for the treatment or prevention of cardiac arrhythmia. Can. Pat. Appl. (1996), CA 2154807 A1 19960223.
[3] Castro, Bertrand; Dormoy, Jean-Robert; Mach, Mateusz; Makosza, Mieczyslaw; Pankowski, Jacek; Preparation of 2-oxazolinyl-4'-phthalimidomethylbiphenyls. PCT Int. Appl. (1999), WO 9906398 A1 19990211.
[4] Nisnevich, Gennady; Rukhman, Igor; Pertsikov, Boris; Kaftanov, Julia; Dolitzky, Ben-Zion; Shapiro, Eugeny; Yahalomi, Bonit; Synthesis of irbesartan. PCT Int. Appl. (2004), WO 2004007482 A2 20040122.

GLOBALLY HARMONIZED SYSTEM (GHS)

Pictograms

Signal Word
Warning

Hazard Statements
H315; H319; H335

Precautionary Statements
P261; P264; P271; P280; P302+P352; P304+P340; P305+P351+P338; P312; P321; P332+P313; P337+P313; P362; P403+P233; P405; P501


Current as of January 1, 2025


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All products are stocked and shipped from the SF Bay, California, USA via FedEx, UPS or DHL.
All batches backed with full quality assurance.
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All products are for research and development use only, not for any other uses, and must be handled by technically-qualified persons.

These products are explicitly not intended to be used in foods and/or cosmetics and/or drugs (human and veterinary) and/or consumer products and/or biocides and/or pesticides of any kind unless explicitly stated otherwise.

Products are not sold to individuals. We do not ship to residential addresses. Consumer orders will be cancelled without notice.

New customers undergo an internal onboarding process. As part of this process, new customers may be asked for more information. Additional restrictions may apply.



CATEGORIES

 APIs and Bioactives > Angiotensin Receptor Blockers, Hypertension


PubChem
  @PubMed
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