REVIEW Pseudotropine (Tropine or 3-tropanol) is a derivative of tropane, a plant alkaloid, containing a hydroxyl group at third carbon, and is used a synthetic building block in drug discovery against a range of therapeutically interesting targets.
REFERENCES
[1]
Barrowcliff, M.; Tutin, F. Configuration of Tropine and 3-Tropine, and the Resolution of Atropine. Proceedings of the Chemical Society, London (1910), 25, 256.
[2]
Fodor, G.; Nador, K. Stereochemistry of tropine and pseudotropine. Nature (London, United Kingdom) (1952), 169, 462-3.
[3]
Novak, M.; Salemink, C. A.; Khan, I. Biological activity of the alkaloids of Erythroxylum coca and Erythroxylum novogranatense. Journal of Ethnopharmacology (1984), 10(3), 261-74.
[4]
John, Varghese; Bredesen, Dale E Tropinol esters and related compounds to promote normal processing of amyloid precursor protein. PCT Int. Appl. (2013), WO 2013019901 A2 20130207.
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