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BIOLOGICAL INFO
Solubility:
EtOH
Application(s):
Nasal Decongestant; Alpha-Adrenoceptor Agonist
Form:
HCl salt
REVIEW Xylometazoline is a drug used as a topical nasal decongestant. The drug works by constricting the blood vessels in the nose by binding to alpha-adrenergic receptors in the nasal mucosa.. The vasoconstriction means that there is less pressure in the capillaries and less water can filter out, thus less discharge is made.
REFERENCES
[1]
Haenisch B, Walstab J, Herberhold S, Bootz F, Tschaikin M, Ramseger R, B?nisch H (2010). Alpha-adrenoceptor agonistic activity of oxymetazoline and xylometazoline. Fundam Clin Pharmacol. 24(6):729-39. PMID 20030735.
[2]
Eskiizmir G, Hir?in Z, Ozyurt B, Unlü H (2011). A comparative analysis of the decongestive effect of oxymetazoline and xylometazoline in healthy subjects. Eur J Clin Pharmacol. 67(1):19-23. PMID 21069518.
[3]
Eccles R, Martensson K, Chen SC (2010). Effects of intranasal xylometazoline, alone or in combination with ipratropium, in patients with common cold. Curr Med Res Opin. 26(4):889-99. PMID 20151787.
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All batches backed with full quality assurance.
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