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  G665    
Olprinone hydrochloride, 98% (HPLC)
 
Loprinone hydrochloride
1,2-Dihydro-5-(imidazo[1,2-a]pyridin-6-yl)-6-methyl-2-oxo-3-pyridinecarbonitrile hydrochloride
IDENTITY
CAS Number:119615-63-3
MDL Number:MFCD01749474
MF:C14H11ClN4O
MW:286.72
SPECIFICATIONS & PROPERTIES
Min. Purity Spec:98% (HPLC)
Physical Form (at 20°C):Solid
Melting Point:>300°C
Long-Term Storage:Store long-term at 2-8°C
DOT/IATA TRANSPORT INFORMATION
Not hazardous material

BIOLOGICAL INFO
Solubility:DMSO: <=4mg/mL; H2O: 7mg/mL
Application(s):Cardiotonic Agent; Phosphodiesterase 3 Inhibitor
Form:HCl salt

REVIEW
 Olprinone is a cardiotonic agent. It is a selective phosphodiesterase 3 (PDE3) inhibitor.

REFERENCES
[1]Genovese T, Mazzon E, Paterniti I, Esposito E, Cuzzocrea S (2011). Neuroprotective effects of olprinone after cerebral ischemia/reperfusion injury in rats. Neurosci Lett. 503(2):93-9. PMID 21872644.
[2] Kinouchi K, Morita K, Ko Y, Nagahori R, Shinohara G, Abe T, Hashimoto K (2012). Reversal of oxidant-mediated biochemical injury and prompt functional recovery after prolonged single-dose crystalloid cardioplegic arrest in the infantile piglet heart by terminal warm-blood cardioplegia supplemented with phosphodiesterase III inhibitor. Gen Thorac Cardiovasc Surg. 60(2):73-81. PMID 22327851.

GLOBALLY HARMONIZED SYSTEM (GHS)

Pictograms

Signal Word
Warning

Hazard Statements
H315; H319; H335

Precautionary Statements
P261; P264; P271; P280; P302+P352; P304+P340; P305+P351+P338; P312; P321; P332+P313; P337+P313; P362; P403+P233; P405; P501

Current as of January 28, 2025


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All products are stocked and shipped from the SF Bay, California, USA via FedEx, UPS or DHL.
All batches backed with full quality assurance.
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All products are for research and development use only, not for any other uses, and must be handled by technically-qualified persons.

These products are explicitly not intended to be used in foods and/or cosmetics and/or drugs (human and veterinary) and/or consumer products and/or biocides and/or pesticides of any kind unless explicitly stated otherwise.

Products are not sold to individuals. We do not ship to residential addresses. Consumer orders will be cancelled without notice.

New customers undergo an internal onboarding process. As part of this process, new customers may be asked for more information. Additional restrictions may apply.


CATEGORIES
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