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  O626    
Nomilin
, 98% (HPLC)
 
1-(Acetyloxy)-1,2-dihydroobacunoic acid e-lactone




IDENTITY
CAS Number:1063-77-0
MDL Number:MFCD00075979
MF:C28H34O9
MW:514.56
SPECIFICATIONS & PROPERTIES
Min. Purity Spec:98% (HPLC)
Physical Form (at 20°C):Solid
Melting Point:259-263°C
Optical Rotation:-78.5° (c=1, Acetone)
Long-Term Storage:Store long-term at 2-8°C
DOT/IATA TRANSPORT INFORMATION
Not hazardous material

BIOLOGICAL INFO
Application(s):Carciogenesis inhibitor, A inducer of phase II detoxifying enzymes

REVIEW

 Nomilin is a natural product isolated from grapefruit seed and varying Citrus fruits. The compound is an inducer of Phase II detoxifying enzymes and inhibitor of chemically induced carcinogenesis. The compound has been observed to have 2.9-8.3 times the antioxidant activity when compared to Vitamin C. Nomilin has also been documented to inhibit HIV-1 injection in human mononuclear cells. In a dose dependent manner Nomilin has increased the activity of GST in the liver of rats.

REFERENCES
[1]Miller, E.G., et al. 1989. Carcinogenesis. 10: 1535-1537. PMID: 2502323
[2] Battinelli, L., et al. 2003. Planta Med. 69: 910-913. PMID: 14648393
[3] Poulose, S.M., et al. 2006. Nutr Cancer. 56: 103-112. PMID: 17176224
[4] Perez, J.L., et al. 2010. BMC Complement Altern Med. 10: 51. PMID: 20846448

GLOBALLY HARMONIZED SYSTEM (GHS)

Pictograms

Signal Word
Warning

Hazard Statements
H315; H319; H335

Precautionary Statements
P261; P264; P271; P280; P302+P352; P304+P340; P305+P351+P338; P312; P321; P332+P313; P337+P313; P362; P403+P233; P405; P501


Current as of December 29, 2024


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All products are stocked and shipped from the SF Bay, California, USA via FedEx, UPS or DHL.
All batches backed with full quality assurance.
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All products are for research and development use only, not for any other uses, and must be handled by technically-qualified persons.

These products are explicitly not intended to be used in foods and/or cosmetics and/or drugs (human and veterinary) and/or consumer products and/or biocides and/or pesticides of any kind unless explicitly stated otherwise.

Products are not sold to individuals. We do not ship to residential addresses. Consumer orders will be cancelled without notice.

New customers undergo an internal onboarding process. As part of this process, new customers may be asked for more information. Additional restrictions may apply.



CATEGORIES

 APIs and Bioactives > Natural Products


PubChem
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