Zinc Protoporphyrin NEW
| Price | $42 | $64 | $158 |
| Package | 5mg | 10mg | 50mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-06-11 |
Product Details
| Product Name: Zinc Protoporphyrin | CAS No.: 15442-64-5 |
| Purity: 99.27% | Supply Ability: 10g |
| Release date: 2025/06/11 |
Product Introduction
Bioactivity
| Name | Zinc Protoporphyrin |
| Description | Zinc Protoporphyrin (Zn(II)-protoporphyrin IX) is an orally active, competitive inhibitor of heme oxygenase-1 (HO-1) that markedly attenuates the protective effects of Phloroglucinol (PG) against H2O2 and exhibits anti-cancer activity. |
| In vitro | Zinc Protoporphyrin (Zn(II)-protoporphyrin IX; 5 μM; 72 hours) increased the proportion of late apoptosis and necrotic cells from 10.9% in the control group to 30.4% after 72 hours [3]. Zinc Protoporphyrin (1.25-40 μM; 48 or 72 hours) exerts cystostatic/cytotoxic effects against tumor cells[3]. Zinc Protoporphyrin (2.5, 5 μM; 48 or 72 hours) results in dose- and time-dependent reduction of cells in G1 phase of the cell cycle[3]. Zinc Protoporphyrin (1.25-40 μM; 48 hours) leads to accumulation of cleaved (active) caspase-3[3]. |
| In vivo | Zinc Protoporphyrin exhibits dose-dependent antitumor effects manifested by the retardation of tumor growth[3]. |
| Storage | keep away from direct sunlight,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | DMSO : 50 mg/mL (79.87 mM), Sonication is recommended. H2O : < 0.1 mg/mL (insoluble) |
| Keywords | Zinc Protoporphyrin9 | Zinc Protoporphyrin 9 | Zinc Protoporphyrin | screening | ReactiveOxygenSpecies | Reactive Oxygen Species | Phloroglucinol | oxygenase-1 | marker | iron | Inhibitor | inhibit | Human Endogenous Metabolite | HO-1 | heme | H2O2 | EndogenousMetabolite | Endogenous Metabolite | deficiency,anti-cancer | Apoptosis |
| Inhibitors Related | Sucrose | Cysteamine hydrochloride | Daidzein | Fumaric acid | Guanidine hydrochloride | Tributyrin | Ferulic Acid | Glycerol | Thymidine | Naringin | Alginic acid | 3-Indoleacetic acid |
| Related Compound Libraries | Apoptosis Compound Library | NF-κB Signaling Compound Library | Bioactive Compound Library | Anti-Breast Cancer Compound Library | Inhibitor Library | Anti-Fibrosis Compound Library | Metabolism Compound Library | Immunology/Inflammation Compound Library | Anti-Aging Compound Library | Bioactive Compounds Library Max | Anti-Liver Cancer Compound Library | Anti-Cancer Active Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, USA
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