ZD-0892 NEW
Price | $119 | $293 | $483 |
Package | 1mg | 5mg | 10mg |
Min. Order: | |
Supply Ability: | 10g |
Update Time: | 2024-11-13 |
Product Details
Product Name: ZD-0892 | CAS No.: 171964-73-1 |
Purity: 99.53% | Supply Ability: 10g |
Release date: 2024/11/13 |
Product Introduction
Bioactivity
名稱 | ZD-0892 |
描述 | ZD-0892 is a selective and potent inhibitor of neutrophil elastase, targeting human neutrophil elastase and porcine pancreatic elastase with Kis of 6.7 nM and 200 nM, respectively. |
體外活性 | Neutrophils incubated with ZD-0892 (20μM) for 1 hour were found to be resistant to superoxide, hypochlorite, hydrogen peroxide, hydroxyl radical and peroxynitrite-mediated degradation and had no effect on the formation of these oxidants by activated neutrophils.[3] |
體內(nèi)活性 | Administration of ZD0892 to DBA/2 mice infected with EMC virus reduces myocardial elastolytic activity and coronary microvascular perfusion injury.ZD0892 reduces the pathological severity of myocardial lesions associated with viral myocarditis in mice[1].ZD-0892 reverses advanced pulmonary vascular disease produced in rats[2]. |
存儲條件 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
溶解度 | DMSO : 150 mg/mL (300.29 mM), Sonication is recommended. |
關(guān)鍵字 | ZD-0892 | ZD0892 | ZD 0892 |
相關(guān)產(chǎn)品 | PMSF | Nafamostat mesylate | Diminazene Aceturate | AEBSF hydrochloride | Leupeptin Hemisulfate | 2-(2-bromophenyl)-5-chloro-4H-3,1-benzoxazin-4-one | Ceritinib | Aprotinin | 2,4-Dioxaspiro(5.5)undec-8-ene, 3-(2-furanyl)- | Benzamidine hydrochloride |
相關(guān)庫 | 經(jīng)典已知活性庫 | 已知活性化合物庫 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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- Since: 2011-01-07
- Address: 36?Washington?Street, Wellesley?Hills
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