Zalcitabine NEW
| Price | $30 | $43 | $61 |
| Package | 25mg | 50mg | 100mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-19 |
Product Details
| Product Name: Zalcitabine | CAS No.: 7481-89-2 |
| Purity: ≥95% | Supply Ability: 10g |
| Release date: 2024/11/19 |
Product Introduction
Bioactivity
| Name | Zalcitabine |
| Description | Zalcitabine (Dideoxycytidine)(Dideoxycytidine;ddC; 2', 3'-Dideoxycytidine) is a nucleoside analog reverse transcriptase inhibitor (NRTI); At low concentrations, It can potently inhibit HIV replication by binding to reverse transcriptase terminated synthesis of viral DNA chain. |
| In vitro | Zalcitabine is a dideoxynucleoside antiretroviral agent that is phosphorylated to the active metabolite 2',3'-dideoxycytidine 5'-triphosphate (ddCTP) in both uninfected and HIV-infected cells. At therapeutic concentrations, ddCTP inhibits HIV replication by targeting reverse transcriptase and terminating the elongation of proviral DNA. Zalcitabine also inhibits the cellular uptake of [3H]-PAH in CHO/hOAT1 cells, with an IC50 value of 1.23 mM, and its uptake increases threefold with enhanced hOAT1 activity in these cells. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | DMSO : 60 mg/mL (284.06 mM), Sonication is recommended. |
| Keywords | Reverse Transcriptase | Zalcitabine | NSC606170 | NSC-606170 | inhibit | Human immunodeficiency virus | HIV | Inhibitor |
| Inhibitors Related | Stavudine | 5-Fluorouracil | Emtricitabine | Kaempferol | Dextran sulfate sodium salt (MW 4500-5500) | Lamivudine | Decanedioic acid |
| Related Compound Libraries | Bioactive Compound Library | Hematonosis Compound Library | Anti-Viral Compound Library | Drug Repurposing Compound Library | Drug-Fragment Library | Inhibitor Library | NO PAINS Compound Library | FDA-Approved Drug Library | Bioactive Compounds Library Max | Covalent Inhibitor Library |
Company Profile Introduction
TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds.
170+ Compound Libraries， 10000+ Noval Small Molecucles，16000+ Nature Compounds
TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.
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United States- Since: 2011-01-07
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