Z-Asp-CH2-DCB NEW
Price | $30 | $38 | $63 |
Package | 2mg | 5mg | 10mg |
Min. Order: | |
Supply Ability: | 10g |
Update Time: | 2024-11-19 |
Product Details
Product Name: Z-Asp-CH2-DCB | CAS No.: 153088-73-4 |
Purity: 99.08% | Supply Ability: 10g |
Release date: 2024/11/19 |
Product Introduction
Bioactivity
Name | Z-Asp-CH2-DCB |
Description | Z-Asp-CH2-DCB is an irreversible inhibitor of broad-spectrum caspases. |
In vitro | Z-Asp-CH2-DCB (10-100 μM) dose-dependently inhibits the production of IL-1β, TNF-α, IL-6, and IFN-γ in SEB-stimulated (200 ng) PBMC, and suppresses the chemokines MCP-1, MIP-1α, and MIP-1β[1]. Additionally, Z-Asp-CH2-DCB reduces IL-1β, IL-6, TNF-α, IFN-γ, MCP-1, MIP-1α, and MIP-1β production in TSST-1-activated PBMC to 10%, 36%, 25%, 10%, 11%, 25%, and 30%, respectively[1]. |
In vivo | SU5416-induced septal cell apoptosis prevented byZ-Asp-CH2-DCB (1 mg; i.p.; every day for 3 weeks)[1]. |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Solubility Information | DMSO : 95.4 mg/mL (210 mM), Sonication is recommended. |
Keywords | ZAspCH2DCB | Z Asp CH2 DCB | Z-Asp-CH2-DCB | Z-Asp-CH-2-DCB |
Related Compound Libraries | Bioactive Compound Library | Bioactive Compounds Library Max | Covalent Inhibitor Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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- Since: 2011-01-07
- Address: 36?Washington?Street, Wellesley?Hills
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