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Postion:Product Catalog >YHO-13351 free base
YHO-13351 free base
  • YHO-13351 free base

YHO-13351 free base NEW

Price $30 $64 $106
Package 1mg 5mg 10mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-19

Product Details

Product Name: YHO-13351 free base CAS No.: 912288-64-3
Purity: 100% Supply Ability: 10g
Release date: 2024/11/19

Product Introduction

Bioactivity

NameYHO-13351 free base
DescriptionYHO-13351 free base, the water-soluble prodrug of YHO-13177, is an inhibitor of BCRP (breast cancer resistance protein).
In vivoIn mice, YHO-13351 was rapidly converted into YHO-13177 after its oral or intravenous administration. Coadministration of Irinotecan Hydrochloride with YHO-13351 significantly increased the survival time of mice inoculated with BCRP-transduced murine leukemia P388 cells and suppressed the tumor growth in an HCT116/BCRP xenograft model, whereas Irinotecan Hydrochloride alone had little effect in these tumor models[1].
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility InformationDMSO : 90 mg/mL (186.1 mM), Sonication is recommended.
KeywordsYHO-13351 | YHO 13351 free base | YHO13351 | YHO 13351 | YHO-13351 free base | YHO13351 free base
Inhibitors RelatedGS-9191 PM | Brevianamide F | ABCG2-IN-2 | Zamicastat | PCI 29732 | CP-100356 hydrochloride | Elacridar | YHO-13177 | 6,8-Diprenylnaringenin | Ko 143 | Triclabendazole sulfoxide | KS176
Related Compound LibrariesBioactive Compound Library | Bioactive Compounds Library Max | Covalent Inhibitor Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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  • Since: 2011-01-07
  • Address: 36?Washington?Street, Wellesley?Hills
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