YAP/TAZ inhibitor-2? NEW
Price | $84 | $122 | $197 |
Package | 1mg | 2mg | 5mg |
Min. Order: | |
Supply Ability: | 10g |
Update Time: | 2024-11-19 |
Product Details
Product Name: YAP/TAZ inhibitor-2? | CAS No.: 2762617-31-0 |
Purity: 98.84% | Supply Ability: 10g |
Release date: 2024/11/19 |
Product Introduction
Bioactivity
Name | YAP/TAZ inhibitor-2? |
Description | YAP/TAZ inhibitor-2 is a potent, orally active TEAD-YAP/TAZ inhibitor with an EC50 value of 3 nM, demonstrating anti-proliferative and antitumor activity [1]. |
In vitro | YAP/TAZ inhibitor-2 (compound 5) exhibits antiproliferative activity in NCI-H226 cells, with an IC50 value of 5.33 nM over 24 hours at concentrations ranging from 0 to 20000 nM [1]. |
In vivo | YAP/TAZ inhibitor-2 (0.5, 2, 5, 50 mg/kg; p.o.; daily for 28 days) exhibits anti-tumor activity without significant body weight loss during the treatment in BALB/c nude mice (NCI-H226 xenograft model) [1]. |
Storage | Shipping with blue ice. |
Solubility Information | DMSO : 90 mg/mL (230.6 mM), Sonication is recommended. |
Keywords | YAP/TAZ inhibitor-2 | YAP/TAZinhibitor2? |
Inhibitors Related | AICAR | MY-1076 | YAP-TEAD-IN-3 | DC-TEADin02 | Verteporfin | Lats-IN-1 | VT103 | VT107 | ML-7 hydrochloride | PY-60 | VT104 | MYF-01-37 |
Related Compound Libraries | Bioactive Compound Library | Inhibitor Library | Bioactive Compounds Library Max | Anti-Cancer Compound Library | Anti-Cancer Active Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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- Since: 2011-01-07
- Address: 36?Washington?Street, Wellesley?Hills
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