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Postion:Product Catalog >YAP/TAZ inhibitor-2?
YAP/TAZ inhibitor-2?
  • YAP/TAZ inhibitor-2?

YAP/TAZ inhibitor-2? NEW

Price $84 $122 $197
Package 1mg 2mg 5mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-19

Product Details

Product Name: YAP/TAZ inhibitor-2? CAS No.: 2762617-31-0
Purity: 98.84% Supply Ability: 10g
Release date: 2024/11/19

Product Introduction

Bioactivity

NameYAP/TAZ inhibitor-2?
DescriptionYAP/TAZ inhibitor-2 is a potent, orally active TEAD-YAP/TAZ inhibitor with an EC50 value of 3 nM, demonstrating anti-proliferative and antitumor activity [1].
In vitroYAP/TAZ inhibitor-2 (compound 5) exhibits antiproliferative activity in NCI-H226 cells, with an IC50 value of 5.33 nM over 24 hours at concentrations ranging from 0 to 20000 nM [1].
In vivoYAP/TAZ inhibitor-2 (0.5, 2, 5, 50 mg/kg; p.o.; daily for 28 days) exhibits anti-tumor activity without significant body weight loss during the treatment in BALB/c nude mice (NCI-H226 xenograft model) [1].
StorageShipping with blue ice.
Solubility InformationDMSO : 90 mg/mL (230.6 mM), Sonication is recommended.
KeywordsYAP/TAZ inhibitor-2 | YAP/TAZinhibitor2?
Inhibitors RelatedAICAR | MY-1076 | YAP-TEAD-IN-3 | DC-TEADin02 | Verteporfin | Lats-IN-1 | VT103 | VT107 | ML-7 hydrochloride | PY-60 | VT104 | MYF-01-37
Related Compound LibrariesBioactive Compound Library | Inhibitor Library | Bioactive Compounds Library Max | Anti-Cancer Compound Library | Anti-Cancer Active Compound Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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