VU 0240551 NEW
| Price | $31 | $71 | $127 |
| Package | 1mg | 5mg | 10mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-19 |
Product Details
| Product Name: VU 0240551 | CAS No.: 893990-34-6 |
| Purity: 99.72% | Supply Ability: 10g |
| Release date: 2024/11/19 |
Product Introduction
Bioactivity
| Name | VU 0240551 |
| Description | VU 0240551 is a selective antagonist of neuronal K-Cl cotransporter KCC2 inhibitor with an IC50 of 560 nM. VU 0240551 inhibits L-type calcium channels and hERG. |
| In vitro | VU 0240551 (0-100 μM) reduces the P cell response to GABA in a concentration-dependent manner and significantly reduces GABA-elicited hyperpolarization at doses of 75 and 100 μM[3]. |
| In vivo | VU 0240551 (10 μM) significantly inhibits chloride influx in cells from euhydrated rats, but does not affect cells from salt-loaded rats[4]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | H2O : Insoluble DMSO : 45 mg/mL (131.41 mM), Sonication is recommended. |
| Keywords | VU 0240551 | VU0240551 | VU-0240551 |
| Inhibitors Related | Minoxidil sulfate | Nisoldipine | Diltiazem hydrochloride | Levetiracetam | L-Ascorbic acid | Lanthanum(III) chloride heptahydrate | Halothane | Neratinib | Ethyl cinnamate | 1-Octanol | Cloperastine hydrochloride | Indapamide |
| Related Compound Libraries | Anti-Lung Cancer Compound Library | Anti-Pancreatic Cancer Compound Library | Bioactive Compound Library | Pain-Related Compound Library | Neuronal Signaling Compound Library | Membrane Protein-targeted Compound Library | Tyrosine Kinase Inhibitor Library | Inhibitor Library | Bioactive Compounds Library Max | Ion Channel Targeted Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36?Washington?Street, Wellesley?Hills
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