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Postion:Product Catalog >API>Blood System Drugs>voxelotor
voxelotor
  • voxelotor

voxelotor NEW

Price $33 $51 $74
Package 2mg 5mg 10mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-15

Product Details

Product Name: voxelotor CAS No.: 1446321-46-5
Purity: 99.94% Supply Ability: 10g
Release date: 2024/11/15

Product Introduction

Bioactivity

名稱voxelotor
描述Voxelotor (GBT 440) is a novel hemoglobin S (HbS) polymerization inhibitor primarily used for the treatment of sickle cell disease (SCD) and a cytochrome P450 3A4 inhibitor. Voxelotor targets and covalently binds to the N-terminal valine of the HbS alpha chain, thereby stabilizing sickle cell hemoglobin (HbS).
體內(nèi)活性Voxelotor?treatment reduced bilirubin levels and improved jaundice[1].
存儲條件store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
溶解度DMSO : 125 mg/mL (370.51 mM)
關(guān)鍵字GBT440 | polymerization | haemoglobin | sickle | GBT-440 | SCD | inhibit | cell | disease | voxelotor | Inhibitor | HbS
相關(guān)庫經(jīng)典已知活性庫 | EMA 上市藥物庫 | 藥物功能重定位化合物庫 | 抑制劑庫 | 抗心血管疾病化合物庫 | FDA 上市藥物庫 | 口服活性化合物庫 | 已知活性化合物庫 | 共價抑制劑庫 | 人代謝物化合物庫

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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