Vipivotide tetraxetan NEW
Price | $193 | $287 | $483 |
Package | 1mg | 2mg | 5mg |
Min. Order: | |
Supply Ability: | 10g |
Update Time: | 2024-11-19 |
Product Details
Product Name: Vipivotide tetraxetan | CAS No.: 1702967-37-0 |
Purity: 98.45% | Supply Ability: 10g |
Release date: 2024/11/19 |
Product Introduction
Bioactivity
Name | Vipivotide tetraxetan |
Description | Vipivotide tetraxetan (PSMA-617) is a highly potent inhibitor of prostate-specific membrane antigen (PSMA) with a Ki of 0.37 nM. |
In vitro | The chemically modified PSMA inhibitor PSMA-617 demonstrated high radiolytic stability for at least 72 h. A high inhibition potency (equilibrium dissociation constant [K(i)] = 2.34 2.94 nM on LNCaP; K(i) = 0.37 0.21 nM enzymatically determined) and highly efficient internalization into LNCaP cells were demonstrated. |
In vivo | The small-animal PET measurements showed high tumor-to-background contrasts as early as 1 h after injection of Vipivotide tetraxetan.Organ distribution revealed specific uptake in LNCaP tumors and in the kidneys 1 h after injection of Vipivotide tetraxetan[1]. |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Solubility Information | DMSO : 100 mg/mL (95.96 mM), Sonication is recommended. H2O : 100 mg/mL (95.96 mM) |
Keywords | Inhibitor | PSMA 617 | Vipivotide tetraxetan | Drug-Linker Conjugates for ADC | inhibit | PSMA617 |
Inhibitors Related | Deruxtecan | Fmoc-Val-Cit-PAB-MMAE | DL-Mannitol | Vc-MMAD | SMCC-DM1 | Mc-VC-PAB-SN38 | VCMMAE | CL2A-SN-38 | Val-Cit-PAB-MMAE | DUPA(OtBu)-OH | McMMAF | Mc-MMAE |
Related Compound Libraries | Bioactive Compound Library | Anti-Cancer Clinical Compound Library | Drug Repurposing Compound Library | Inhibitor Library | Bioactive Compounds Library Max | Anti-Cancer Active Compound Library | Anti-Cancer Drug Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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- Since: 2011-01-07
- Address: 36?Washington?Street, Wellesley?Hills
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