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Postion:Product Catalog >UNC926 hydrochloride
UNC926 hydrochloride
  • UNC926 hydrochloride

UNC926 hydrochloride NEW

Price $80 $181 $272
Package 1mg 5mg 10mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-19

Product Details

Product Name: UNC926 hydrochloride CAS No.: 1782573-49-2
Purity: 98.71% Supply Ability: 10g
Release date: 2024/11/19

Product Introduction

Bioactivity

NameUNC926 hydrochloride
DescriptionUNC926 hydrochloride is a methyl-lysine (Kme) reader domain inhibitor.
In vitroUNC926 demonstrates a low micromolar affinity toward L3MBTL3, exhibiting an IC50 of 3.2 μM, and shows diminished affinity for other MBT domains without binding to CBX7. In a concentration-dependent manner ranging from 1-25 μM, UNC926 effectively inhibits the interaction between the 3xMBT domain and H4K20me1 and impedes the association of L3MBTL1's 3xMBT with specific histone peptides. However, it does not disrupt the binding of 53BP1 to H4K20me1, indicating that UNC926 specifically targets L3MBTL1 rather than 53BP1.
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility InformationDMSO : 150 mg/mL (444.77 mM)
KeywordsUNC-926 hydrochloride | UNC-926 Hydrochloride | UNC926 Hydrochloride | UNC926 hydrochloride | UNC-926 | UNC926 | UNC 926 Hydrochloride | UNC 926 | methyl-lysine | L3MBTL3 | L3MBTL1 | Inhibitor | inhibit | H4K20me1 | Epigenetic Reader Domain | 3xMBT
Inhibitors RelatedABBV-744 | CeMMEC1 | 3-methyl-1,2,3,4-tetrahydroquinazolin-2-one | (+)-JQ-1 | J-147 | Anacardic Acid | Curcumin | dBET6 | Piflufolastat | Naphthol AS-E | Bisdemethoxycurcumin | GSK1379725A
Related Compound LibrariesHistone Modification Compound Library | Bioactive Compound Library | Epigenetics Compound Library | Inhibitor Library | NO PAINS Compound Library | Bioactive Compounds Library Max

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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