Product Details
Product Name:
UNC-2170 |
CAS No.:
1648707-58-7 |
Purity:
98.83% |
Supply Ability:
10g |
Release date:
2024/11/19 |
Product Introduction
Bioactivity
Name | UNC-2170 |
Description | UNC-2170 (UNC2170 Maleate) is the methyl-lysine binding protein, 53BP1 ligand. |
In vitro | UNC-2170 (500 μM) results in a significant increase in soluble 53BP1 as compared to lysates treated with UNC2892, the negative control compound. UNC-2170 (30-100 μM; naive splenocytes cultured with LPS and IL-4 for 3.5 days) clearly phenocopies the reduction in CSR seen in 53BP1 mutant B cells[1]. |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Solubility Information | DMSO : 60 mg/ml (191.55 mM), Sonication is recommended. Methanol : 125 mg/mL (399.07 mM), Sonication is recommended.
|
Keywords | Kme readers | tudor domain | UNC2170 | H4K20me2 | ligand | 53BP1 | UNC-2170 | inhibit | double-strand DNA breaks | UNC 2170 | Inhibitor |
Related Compound Libraries | Bioactive Compound Library | Bioactive Compounds Library Max |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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