Manufacturer Provide Veterinary Medicine Raw Powder CAS63428-13-7 Tylvalosin Tartrate

Introduction

1.Product Name: Tylvalosin Tartrate

2.Other name: Acetylisovaleryltylosin Tartrate/Tylosin 3-acetate 4B-(3-methylbutanoate) (2R,3R)-2,3-dihydroxybutanedioate

3.CAS NO:63428-13-7

4.Purity: 99%min

5.Appearance:White Powder

6.Molecular formula: C57H93NO25

7.EINECS NO. :256-145-7

8.Molecular weight：1192.35

9.Melting Point :208 - 211°C(lit.)

10.Storage:Keep in a cool, dry, dark location

Pharmacological Actions:Pharmacodynamics: Tylosin is an animal-specific macrolide antibiotic, which has a strong effect on mycoplasma. The antibacterial spectrum is similar to erythromycin. The sensitive gram-positive bacteria include Staphylococcus aureus (including penicillin-resistant Staphylococcus aureus), pneumococcus, streptococcus, Bacillus anthracis, Erysipelas, Listeria, and Clostridium putrefaction , Clostridium emphysema, etc. Sensitive gram-negative bacteria include Haemophilus, meningococcus, and Pasteurella. Sensitive bacteria can develop resistance to this product, and Staphylococcus aureus has partial cross-resistance to this product and erythromycin. 
Pharmacokinetics: Tylosin can be absorbed from the gastrointestinal tract after oral administration, and the peak blood concentration of pigs is reached within 1 hour after oral administration. Tylosin phosphate is less absorbed. Tylosin is widely distributed in the body after being absorbed, and the organ concentration for injection is 2-3 times higher by oral administration, but it is not easy to penetrate into the cerebrospinal fluid. 
Drug Interaction:  
(1) It is not suitable to be used at the same time as other macrolides, lincosamides and chloramphenicols have the same target. 
(2) Combined use with β-lactams shows antagonism. 
Function and Use:  Macrolide antibiotics. Used for poultry Gram-positive bacteria and mycoplasma infection.