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Postion:Product Catalog >TX1-85-1
TX1-85-1
  • TX1-85-1

TX1-85-1 NEW

Price $64 $129 $228
Package 1mg 5mg 10mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-18

Product Details

Product Name: TX1-85-1 CAS No.: 1603845-32-4
Purity: 98.12% Supply Ability: 10g
Release date: 2024/11/18

Product Introduction

Bioactivity

名稱TX1-85-1
描述TX1-85-1 induces partial degradation of Her3 protein and attenuates Her3-dependent signaling. TX1-85-1 is an irreversible Her3 inhibitor (IC50: 23 nM). TX1-85-1 is also the first selective Her3 ligand, which forms a covalent bond with Cys721 located in the ATP-binding site of Her3.
體外活性TX1-85-1 has an anti-proliferation (EC50s: 9.9, 11.5, and 16.9 μM for Ovcar8, HCC827 GR6, and PC9 GR4 cells, respectively) [1].
存儲(chǔ)條件Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
溶解度DMSO : 3.85 mg/mL (6.63 mM), Sonication is recommended.
關(guān)鍵字inhibit | TX1851 | ErbB-1 | Epidermal growth factor receptor | Inhibitor | HER1 | TX1 85 1 | TX-1-85-1 | TX1-85-1 | EGFR
相關(guān)產(chǎn)品Osimertinib | Lidocaine Hydrochloride hydrate | Lapatinib | Afatinib Dimaleate | Erlotinib hydrochloride | Erlotinib | Neratinib | Chalcone | Osimertinib mesylate | Genistein | Khellin | Gefitinib
相關(guān)庫半胱氨酸共價(jià)化合物庫 | 經(jīng)典已知活性庫 | 膜蛋白靶向化合物庫 | 激酶抑制劑庫 | 酪氨酸激酶分子庫 | JAK-STAT 化合物庫 | 血管生成庫 | 抑制劑庫 | NO PAINS 化合物庫 | 已知活性化合物庫

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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