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Postion:Product Catalog >TWSG1 Protein, Mouse, Recombinant (His)
TWSG1 Protein, Mouse, Recombinant (His)
  • TWSG1 Protein, Mouse, Recombinant (His)

TWSG1 Protein, Mouse, Recombinant (His) NEW

Price $600
Package 100μg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-18

Product Details

Product Name: TWSG1 Protein, Mouse, Recombinant (His) Supply Ability: 10g
Release date: 2024/11/18

Product Introduction

Bioactivity

NameTWSG1 Protein, Mouse, Recombinant (His)
DescriptionTWSG1 belongs to the twisted gastrulation protein family. TWSG1 from different species are functionally equivalent. In contrast to Drosophila where TWSG1 expression is limited to early embryos, expression of TWSG1 is found throughout mouse and human development. Mutations in the TWSG1 gene cause at least some of the cells on the dorsal half of the embryo to adopt more ventral cell fates. This is thought to involve gradients of the signaling molecule decapentaplegic. TWSG1 may function as a bone morphogenetic protein signalling agonist or antagonize these activities. It can dislodge latent bone morphogenetic proteins and thus provides a permissive signal that allows high BMP signaling in the embryo. TWSG1 is a cofactor in the antagonism of chordin to BMP signaling. It also binds both the vertebrate Decapentaplegic ortholog BMP4 and chordin and forms ternary complexes. Meanwhile, TWSG1 increases binding of chordin to BMP4, potentiates the ability of chordin to induce secondary axes in Xenopus embryos, and enhances chordin cleavage by vertebrate proteases related to tolloid at a site poorly used in the absence of TWSG1. The presence of TWSG1 enhances the secondary axis-inducing activity of 2 products of chordin cleavage.
StorageShipping with blue ice.
Keywordstwisted gastrulation homolog 1 | Drosophila | AW-552143 | AW 552143

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

Recommended supplier

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$2300.00/1mg
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BINBO BIOLOGICAL CO.,LTD
2024-11-06
  • Since: 2011-01-07
  • Address: 36?Washington?Street, Wellesley?Hills
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