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Postion:Product Catalog >API>Antibiotics>Other antibiotic Drugs>Tulathromycin A
Tulathromycin A
  • Tulathromycin A

Tulathromycin A NEW

Price $48 $77 $118
Package 25mg 50mg 100mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-19

Product Details

Product Name: Tulathromycin A CAS No.: 217500-96-4
Purity: 99.46% Supply Ability: 10g
Release date: 2024/11/19

Product Introduction

Bioactivity

NameTulathromycin A
DescriptionTulathromycin A (CP 472295) is a macrolide antibiotic.
In vitro145 calves were inoculated by two highly pathogenic strains of M. bovis (with minimum inhibitory concentration values for tulathromycin of 1 and >64 μg/ml). Four days after inoculation, calves with clinical BRD were treated subcutaneously with saline or tulathromycin (2.5 mg/kg). Compared with saline, BRD-related withdrawals, peak rectal temperatures, and lung lesion scores were significantly lower for tulathromycin-treated calves (P < .01). Tulathromycin was highly effective in the treatment of BRD due to M. bovis in calves regardless of the minimum inhibitory concentration of the challenge strain (1 or >64 μg/ml). The MIC90 for tulathromycin were 1 μg/ml for Pasteurella multocida (bovine), 2 μg/ml for Mannheimia (Pasteurella) haemolytica, and 2 μg/ml for Pasteurella multocida (porcine) and ranged from 4-16 μg/ml for Actinobacillus pleuropneumoniae and from 0.5-4 μg/ml for Histophilus somni (Haemophilus somnus).
In vivoEach study randomly allocated 250 calves to receive tulathromycin at 2.5 mg/kg and 250 calves to receive either florfenicol at 40 mg/kg or tilmicosin at 10 mg/kg on arrival at the feedlot. Calves were housed by treatment group in pens with 50 calves/pen. The treatment groups were physiologic saline (n=160) given SC at 0.02 ml/kg, tulathromycin (n=20) given SC at 2.5 mg/kg, and tilmicosin (n = 320) given SC at 10 mg/kg.
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility InformationDMSO : 60 mg/mL (74.43 mM)
Keywordsinhibit | Bacterial | pneumonia | CP472295 | swine | Inhibitor | cattle | leukocytes | Antibiotic | ribosome | Tulathromycin A | CP-472295
Inhibitors RelatedNeomycin sulfate | Ampicillin sodium | Kanamycin sulfate | Sulfamethoxazole sodium | Doxycycline | Dimethyl sulfoxide
Related Compound LibrariesMacrocyclic Compound Library | Bioactive Compound Library | Drug-induced Liver Injury (DILI) Compound Library | ReFRAME Related Library | Antibiotics Library | Inhibitor Library | Anti-Bacterial Compound Library | Bioactive Compounds Library Max | Covalent Inhibitor Library | Anti-Infection Compound Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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