Product Details
Product Name:
TUG-424 |
CAS No.:
1082058-99-8 |
Purity:
99.77% |
Supply Ability:
10g |
Release date:
2024/11/12 |
Product Introduction
Bioactivity
名稱 | TUG-424 |
描述 | TUG-424 significantly enhances glucose-stimulated insulin secretion at 100 nM. TUG-424 is a potent and selective free fatty acid receptor 1 agonist (EC50: 32 nM). |
體外活性 | At equivalent glucose concentrations, TUG-424's roughly double enhancement of secretion in the context of 12 mM glucose parallels the effect triggered by palmitate. Increasing TUG-424 doses (100 nM to 10 μM) significantly boost glucose-stimulated insulin secretion, beginning notably at 100 nM and peaking at 3 μM. Additionally, TUG-424 slightly yet significantly diminishes basal insulin secretion at 2.8 mM glucose [1]. |
存儲條件 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
溶解度 | DMSO : 50 mg/mL (189.16 mM)
|
關鍵字 | TUG 424 | TUG-424 |
相關庫 | 經(jīng)典已知活性庫 | 已知活性化合物庫 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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Recommended supplier
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$2800.00/100mg |
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