TT-10 NEW
Price | $34 | $80 | $128 |
Package | 1mg | 5mg | 10mg |
Min. Order: | |
Supply Ability: | 10g |
Update Time: | 2024-11-19 |
Product Details
Product Name: TT-10 | CAS No.: 2230640-94-3 |
Purity: 99.29% | Supply Ability: 10g |
Release date: 2024/11/19 |
Product Introduction
Bioactivity
Name | TT-10 |
Description | TT-10 (TAZ-K), an activator of YES-associated protein (YAP)-transcriptional enhancer factor domain (TEAD) activity, has potential application in heart disease research, specifically for conditions characterized by loss of cardiomyocytes. |
In vitro | TT-10 (10?μmol/L ; 48 h) significantly promoted cell cycle activation and cell division of human induced pluripotent stem cell (hiPSC) derived cardiomyocytes (hiPSCM).[1] |
In vivo | TT-10 (2 μM, 10 μM, 20 μM, or 100 μM ; 48 h ; intraperitoneal injections) was administered to infarcted mouse hearts, the treatment promoted cardiomyocyte proliferation and was associated with declines in infarct size 1 week after administration, but cardiac function worsened at later time points.[2] |
Storage | Shipping with blue ice. |
Solubility Information | DMSO : 11 mg/mL (38.82 mM) |
Keywords | TT 10 | TT10 | TT-10 |
Inhibitors Related | AICAR | MY-1076 | YAP-TEAD-IN-3 | DC-TEADin02 | Verteporfin | Lats-IN-1 | VT103 | VT107 | ML-7 hydrochloride | PY-60 | VT104 | MYF-01-37 |
Related Compound Libraries | Bioactive Compound Library | Drug Repurposing Compound Library | Bioactive Compounds Library Max | Anti-Cancer Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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