Product Details
| Product Name:
Tricetin |
CAS No.:
520-31-0 |
| Purity:
98.908% |
Supply Ability:
10g |
| Release date:
2024/11/18 |
Product Introduction
Bioactivity
| 名稱 | Tricetin |
| 描述 | Tricetin is a flavonoid isolated from pomegranate.Tricetin is a potent competitive inhibitor of Keap1-Nrf2 protein-protein interaction (PPI) and protects Parkinson's disease patients from 6-OHDA-induced neurotoxicity by activating the Nrf2/HO-1 signaling pathway and blocking mitochondria-dependent apoptotic pathways.Tricetin Inhibits migration and expression of the indicator protease progerin-1 (PS-1) in nasopharyngeal carcinoma through the Akt/GSK-1β pathway.Tricetin inhibits endothelial inflammation induced by oxidized LDL mediated by Egr-1, and protects rat chondrocytes from IL-1β-induced inflammation and apoptosis.Tricetin is an inhibitor of endothelial inflammation induced by oxidized LDL mediated by Egr-1 and protects against IL-1β-induced inflammation and apoptosis. |
| 體外活性 | Tricetin (20, 40, and 80 μM; 4 h) significantly improves 6-OHDA (200?μM)-induced SH-SY5Y cells viability and suppresses mitochondria-mediated apoptosis.[1]
Tricetin (80?μM; 1, 2, and 4?h) markedly decreased the expressions of p-JNK and p-p38.[1] |
| 存儲(chǔ)條件 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| 溶解度 | DMSO : 22.5 mg/mL (74.44 mM)
|
| 關(guān)鍵字 | Tricetin |
| 相關(guān)產(chǎn)品 | Stavudine | 5-Fluorouracil | Myricetin | Sodium 4-phenylbutyrate | L-Ascorbic acid | Dextran sulfate sodium salt (MW 4500-5500) | Metronidazole | Sorafenib | Tributyrin | Curcumin |
| 相關(guān)庫(kù) | 抗癌天然產(chǎn)物庫(kù) | 中藥單體化合物庫(kù) | 風(fēng)味化合物庫(kù) | 植物來(lái)源化合物庫(kù) | 天然產(chǎn)物庫(kù) | 中藥抗炎分子庫(kù) | 抑制劑庫(kù) | 高通量篩選天然產(chǎn)物庫(kù) | 已知活性化合物庫(kù) | 藥食同源庫(kù) |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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Recommended supplier
| Product name |
Price |
|
Suppliers |
Update time |
|
|
$/ |
|
Anhui Ruihan Technology Co., Ltd
|
2023-08-21 |
United States