TR antagonist 1 NEW
Price | $299 |
Package | 1mg |
Min. Order: | |
Supply Ability: | 10g |
Update Time: | 2024-11-19 |
Product Details
Product Name: TR antagonist 1 | CAS No.: 500794-88-7 |
Purity: 99.57% | Supply Ability: 10g |
Release date: 2024/11/19 |
Product Introduction
Bioactivity
Name | TR antagonist 1 |
Description | TR antagonist 1 is a highly potent thyroid hormone receptor (TR) antagonist (IC50 of 36 and 22 nM for TRα and TRβ, respectively) that can be used to study diseases caused by endocrine abnormalities. |
In vitro | TR antagonist 1 is a high-affinity thyroid hormone receptor (TR) antagonist with IC50 s of 36 and 22 nM for TRα and TRβ, respectively[1]. |
In vivo | In the cholesterol-fed rat model, treatment with TR antagonist 1 reduces heart rate and shows a tendency to increase the proportion of low-density lipoprotein cholesterol (LDL-C) to a certain extent [1]. |
Storage | keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Solubility Information | DMSO : 50 mg/mL (89.13 mM), Sonication is recommended. |
Keywords | TR antagonist 1 |
Inhibitors Related | Propylthiouracil | Liothyronine | L-Thyroxine | L-Thyroxine sodium | 2,2-BIS(2-HYDROXY-5-BIPHENYLYL)PROPANE | Resmetirom | Carbimazole | Liothyronine sodium | 2-Thiouracil | Tiratricol |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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- Since: 2011-01-07
- Address: 36?Washington?Street, Wellesley?Hills
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