Tolterodine tartrate NEW
| Price | $48 | $76 | $98 |
| Package | 25mg | 50mg | 100mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-19 |
Product Details
| Product Name: Tolterodine tartrate | CAS No.: 124937-52-6 |
| Purity: 99.62% | Supply Ability: 10g |
| Release date: 2024/11/19 |
Product Introduction
Bioactivity
| Name | Tolterodine tartrate |
| Description | Tolterodine tartrate (PNU-200583E) is a potent antagonist for muscarinic receptor. It show selectivity for the urinary bladder and salivary glands in vivo. |
| In vitro | Tolterodine is a novel muscarinic receptor antagonist for the treatment of symptoms such as overactive bladder and urge incontinence.Tolterodine effectively and competitively inhibited carbamylcholine-induced contractions in guinea pig bladder isolation strips in a concentration-dependent manner.Tolterodine has a high affinity for muscarinic receptors, and its Ki values were 2.7 nM, 1.6 nM, 0.75 nM, 4.8 nM, and 3.3 nM in the bladder, heart,, cortex and human bladder in guinea pigs, respectively. The Ki values of Tolterodine in guinea pig bladder, heart, cerebral cortex, parotid gland and human bladder were 2.7 nM, 1.6 nM, 0.75 nM, 4.8 nM and 3.3 nM, respectively. |
| In vivo | Tolterodine is a novel muscarinic receptor antagonist for the treatment of symptoms such as overactive bladder and urge incontinence.Tolterodine effectively and competitively inhibited carbamylcholine-induced contractions in guinea pig bladder isolation strips in a concentration-dependent manner.Tolterodine has a high affinity for muscarinic receptors, and its Ki values were 2.7 nM, 1.6 nM, 0.75 nM, 4.8 nM, and 3.3 nM in the bladder, heart,, cortex and human bladder in guinea pigs, respectively. The Ki values of Tolterodine in guinea pig bladder, heart, cerebral cortex, parotid gland and human bladder were 2.7 nM, 1.6 nM, 0.75 nM, 4.8 nM and 3.3 nM, respectively. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | Ethanol : 6 mg/mL (12.61 mM) H2O : 14 mg/mL (29.4 mM) DMSO : 88 mg/mL (185 mM) |
| Keywords | Tolterodine tartrate | muscarinic | Kabi 2234 | Inhibitor | salivary | mAChR | Tolterodine | urinary | bladder | Tolterodine Tartrate | receptor | inhibit | glands | Kabi2234 | Muscarinic acetylcholine receptor |
| Inhibitors Related | Adiphenine hydrochloride | Nanofin | Arecoline hydrobromide | Forskolin | CLOZAPINE N-OXIDE | Pilocarpine nitrate | Ribavirin | Adenine | Choline chloride | Propoxur |
| Related Compound Libraries | Bioactive Compound Library | Anti-Neurodegenerative Disease Compound Library | Approved Drug Library | Membrane Protein-targeted Compound Library | Drug-induced Liver Injury (DILI) Compound Library | Anti-Parkinson's Disease Compound Library | Drug Repurposing Compound Library | Inhibitor Library | FDA-Approved Drug Library | Bioactive Compounds Library Max |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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