Tiagabine hydrochloride NEW
| Price | $50 | $63 | $113 |
| Package | 10mg | 25mg | 50mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-05-14 |
Product Details
| Product Name: Tiagabine hydrochloride | CAS No.: 145821-59-6 |
| Purity: 99.09% | Supply Ability: 10g |
| Release date: 2025/05/14 |
Product Introduction
Bioactivity
| Name | Tiagabine hydrochloride |
| Description | Tiagabine hydrochloride (NO050328 hydrochloride) is the hydrochloride salt form of tiagabine, a nipecotic acid derivative with anticonvulsant property. A selective gamma-aminobutyric acid (GABA) reuptake inhibitor. |
| In vitro | Tiagabine is a potent inhibitor of GABA uptake into neurons and glial cells. It is involved in modulating GABA levels, especially in areas such as the hippocampus and thalamus[2]. Tiagabine not only affected the decay kinetics of the IPSCs, it also reduced the frequency of occurrence of both spontaneous and miniature IPSCs[4]. |
| In vivo | Tiagabine offers a significant neuroprotection in global ischemia in gerbils when given 30 min before ischemia but not when given 3 h after ischemia[3]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | DMSO : 41.2 mg/mL (100 mM), Sonication is recommended. H2O : 20.6 mg/mL (50 mM), Sonication is recommended. |
| Keywords | γ-Aminobutyric acid Receptor | Tiagabine | TGB | NO-328 Hydrochloride | NO-328 | NO328 | NO-050328 Hydrochloride | NO-050328 | NO050328 | NO 328 Hydrochloride | NO 328 | NO 050328 Hydrochloride | NO 050328 | Gamma-aminobutyric acid Receptor | GABAReceptor | GABA uptake | GABA Receptor |
| Inhibitors Related | DL-Menthol | Urethane | p-Hydroxybenzaldehyde | β-Alanine | Penicillin G sodium salt | Valproic Acid | Halothane | Chlorothymol | Gabapentin | Nikethamide | (-)-α-Pinene | Methionine |
| Related Compound Libraries | Pain-Related Compound Library | Bioactive Compound Library | Anti-Neurodegenerative Disease Compound Library | Membrane Protein-targeted Compound Library | Anti-Cancer Clinical Compound Library | Drug Repurposing Compound Library | Inhibitor Library | FDA-Approved Drug Library | Anti-Cancer Approved Drug Library | Bioactive Compounds Library Max | Ion Channel Targeted Library | Anti-Cancer Drug Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, MA
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