Thymulin NEW
| Price | $45 | $101 | $153 |
| Package | 1mg | 5mg | 10mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-19 |
Product Details
| Product Name: Thymulin | CAS No.: 63958-90-7 |
| Purity: 99.56% | Supply Ability: 10g |
| Release date: 2024/11/19 |
Product Introduction
Bioactivity
| Name | Thymulin |
| Description | Thymulin is a peptide hormone which is mainly produced by thymic epithelial cells and it has immune-modulatory and anti-inflammatory effects |
| In vitro | The effects of different doses and various timings of thymulin intraperitoneal administration on spinal microglial activity and intracellular pathways in an inflammatory rat model of Complete Freund's adjuvant (CFA).?Thymulin treatment was implemented following CFA-induced inflammation for 21 days.?After conducting behavioral tests (edema and hyperalgesia), the cellular and molecular aspects were examined to detect the thymulin effect on inflammatory factors and microglial activity.?Demonstrated that thymulin treatment notably reduced thermal hyperalgesia and paw edema induced by CFA.?Furthermore, molecular investigations showed that thymulin reduced CFA-induced activation of microglia cells, phosphorylation of p38 MAPK and the production of spinal pro-inflammatory cytokines (TNF-α, IL-6) during the study.?Results suggest that thymulin treatment attenuates CFA-induced inflammation.?This effect may be mediated by inhibition of spinal microglia and production of central inflammatory mediators which seems to be associated with the ability of thymulin to reduce p38 MAPK phosphorylation.?These data provide evidence of the anti-hyperalgesic effect of thymulin on inflammatory pain and characterize some of the underlying spinal mechanisms[1]. |
| Storage | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | H2O : 10 mM DMSO : Insoluble |
| Keywords | Thymulin |
| Inhibitors Related | Benzyl cinnamate | ZLDI-8 | Glimepiride sulfonamide | beta-Escin | 8-Epideoxyloganic acid | Anti-inflammatory agent 36 | Bucolome | Anti-inflammatory agent 35 | Fendosal | Ataquimas | Anti-inflammatory agent 34 | TL4-12 |
| Related Compound Libraries | Bioactive Compound Library | Natural Product Library | Peptide Compound Library | Anti-Fibrosis Compound Library | NO PAINS Compound Library | Natural Product Library for HTS | Anti-Aging Compound Library | Bioactive Compounds Library Max | Human Metabolite Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
You may like
Recommended supplier
| Product name | Price | Suppliers | Update time | |
|---|---|---|---|---|
| $0.00/1Box |
VIP1Y
|
American HealthyMorph LLC
|
2024-12-16 | |
| $10.00/1KG |
VIP6Y
|
Hebei Weibang Biotechnology Co., Ltd
|
2024-11-28 | |
| $30.00/1kg |
VIP1Y
|
Shandong Deshang Chemical Co., Ltd.
|
2024-07-11 | |
| $6.50/10mg |
VIP1Y
|
Hebei Ganmiao New material Technology Co., LTD
|
2024-06-27 | |
| $30.00/1kg |
Ouhuang Engineering Materials (Hubei) Co., Ltd
|
2024-04-23 | ||
| $0.00/1kg |
VIP1Y
|
Shaanxi TNJONE Pharmaceutical Co., Ltd
|
2024-04-17 | |
| $27.00/1box |
VIP1Y
|
Shanghai Getian Industrial Co., LTD
|
2024-04-11 | |
| $0.00/1Box |
VIP1Y
|
Shanghai Affida new material science and technology center
|
2024-04-09 | |
| $1.00/1g |
VIP4Y
|
Dorne Chemical Technology co. LTD
|
2024-03-26 | |
| $30.00/1box |
VIP1Y
|
hebei hongtan Biotechnology Co., Ltd
|
2024-03-20 |
United States- Since: 2011-01-07
- Address: 36?Washington?Street, Wellesley?Hills
INQUIRY