天堂网亚洲,天天操天天搞,91视频高清,菠萝蜜视频在线观看入口,美女视频性感美女视频,95丝袜美女视频国产,超高清美女视频图片

Welcome to chemicalbook!
+1 (818) 612-2111
Inquriy
Try our best to find the right business for you.
Do not miss inquiry messages Please log in to view all inquiry messages.

Welcome back!

RFQ
skype
MY Account
Top
Postion:Product Catalog >Thiourea, N-(4-methoxyphenyl)-N'-[5-(5-nitro-2-furanyl)-1,3,4-thiadiazol-2-yl]-
Thiourea, N-(4-methoxyphenyl)-N'-[5-(5-nitro-2-furanyl)-1,3,4-thiadiazol-2-yl]-
  • Thiourea, N-(4-methoxyphenyl)-N'-[5-(5-nitro-2-furanyl)-1,3,4-thiadiazol-2-yl]-
  • Thiourea, N-(4-methoxyphenyl)-N'-[5-(5-nitro-2-furanyl)-1,3,4-thiadiazol-2-yl]-
  • Thiourea, N-(4-methoxyphenyl)-N'-[5-(5-nitro-2-furanyl)-1,3,4-thiadiazol-2-yl]-
  • Thiourea, N-(4-methoxyphenyl)-N'-[5-(5-nitro-2-furanyl)-1,3,4-thiadiazol-2-yl]-
  • Thiourea, N-(4-methoxyphenyl)-N'-[5-(5-nitro-2-furanyl)-1,3,4-thiadiazol-2-yl]-

Thiourea, N-(4-methoxyphenyl)-N'-[5-(5-nitro-2-furanyl)-1,3,4-thiadiazol-2-yl]- NEW

Price $85 $80 $75
Package 1box 5box 10box
Min. Order: 1box
Supply Ability: 2000box
Update Time: 2024-12-25

Product Details

Product Name: Thiourea, N-(4-methoxyphenyl)-N'-[5-(5-nitro-2-furanyl)-1,3,4-thiadiazol-2-yl]- CAS No.: 2413974-52-2
EC-No.: 974-152-2 Min. Order: 1box
Purity: 99+ Supply Ability: 2000box
Release date: 2024/12/25
Common NameMT-802
CAS Number2231744-29-7Molecular Weight787.82
DensityN/ABoiling PointN/A
Molecular FormulaC41H41N9O8Melting PointN/A
MSDSN/AFlash PointN/A
DescriptionMT-802 is a potent BTK degrader based on PROTAC technology, with a DC50 of 1 nM. MT-802 has potential to treat C481S mutant chronic lymphocytic leukemia (CLL)[1].
Related Catalog
Research Areas >> Cancer
Research Areas >> Inflammation/Immunology
Signaling Pathways >> Protein Tyrosine Kinase/RTK >> Btk
Signaling Pathways >> PROTAC >> PROTAC
Target

DC50: 1 nM (BTK)[1].

In VitroMT-802 degrades BTK with a DC50 of 9.1 nM with maximal degradation being observed by 250 nM[1].
References

[1]. Buhimschi AD, et al. Targeting the C481S Ibrutinib-Resistance Mutation in Bruton's Tyrosine Kinase Using PROTAC-Mediated Degradation. Biochemistry. 2018 Jul 3;57(26):3564-3575.

 Chemical & Physical Properties

Molecular FormulaC41H41N9O8
Molecular Weight787.82
Article illustrationArticle illustrationStorage condition-20°C

Article illustration


Company Profile Introduction

Recommended supplier

Product name Price   Suppliers Update time
$1.80/1KG
VIP5Y
Career Henan Chemica Co
 2020-11-07
$0.00/1g
VIP1Y
Xian confluore Biological Technology Co., Ltd.
 2024-04-01
$0.00/1g
VIP6Y
Shaanxi Dideu Medichem Co. Ltd
 2020-01-06
$2500.00/100mg
VIP1Y
TargetMol Chemicals Inc.
 2024-10-23
  • Since: 2024-04-30
  • Address: Room 815, Block A, Yiyuan International Building, No.319, Xinyi Road, Zhengzhou, Henan Pilot Free Tr
INQUIRY