Thiethylperazine NEW
| Price | $83 | $123 | $218 |
| Package | 5mg | 10mg | 25mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-06 |
Product Details
| Product Name: Thiethylperazine | CAS No.: 1420-55-9 |
| Purity: 98.72% | Supply Ability: 10g |
| Release date: 2024/11/06 |
Product Introduction
Bioactivity
| 名稱 | Thiethylperazine |
| 描述 | Thiethylperazine (Tietilperazina) is an orally available, highly potent D2 receptor and H1 receptor antagonist and selective ABCC1 activator with antimicrobial and antiemetic activity that reduces amyloid β (Aβ) load in mice, is used to relieve vertigo, and can be used in studies of neurological diseases such as Alzheimer's disease and Parkinson's disease. Alzheimer's and Parkinson's diseases. |
| 體外活性 | Thiethylperazine enhances the activity of the antibiotic vancomycin at concentrations as low as 2 μg/mL, and it inhibits vancomycin-sensitive and -resistant Enterococcus strains with MIC values of 8 μg/mL, 16 μg/mL, and 8 μg/mL, respectively[3]. |
| 體內(nèi)活性 | Thiethylperazine (3 mg/kg; intramuscular injection; twice daily; for 30 days) markedly decreases Aβ42 levels in young APP/PS1 mice, utilizing an animal model comprising young mice genetically modified to express the amyloid precursor protein (APPswe) and mutant presenilin-1 (PS1) [2], demonstrating a significant reduction in Aβ42 levels and offering insights into potential therapeutic approaches for Alzheimer's disease. |
| 存儲條件 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| 溶解度 | DMSO : 80 mg/mL (200.19 mM), Sonication is recommended. |
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Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36?Washington?Street, Wellesley?Hills
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