Thiamine nitrate NEW
| Price | $56 |
| Package | 10g |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-19 |
Product Details
| Product Name: Thiamine nitrate | CAS No.: 532-43-4 |
| Purity: 99.76% | Supply Ability: 10g |
| Release date: 2024/11/19 |
Product Introduction
Bioactivity
| Name | Thiamine nitrate |
| Description | Thiamine nitrate (Vitamin B1 nitrate) is an essential vitamin, and can enhance normal neuronal actives. |
| In vitro | In a study examining the effect of dietary Thiamine on homozygous knockout (KO) and knock-in (KI) mice compared to wild-type (WT) mice, it was found that at 7 weeks, Thiamine levels in the blood of KO and KI mice fed a conventional diet were significantly reduced to 0.058±0.051 μM and 0.126±0.092 μM, respectively, in contrast to WT mice (0.796±0.259 μM). Further, when subjected to a Thiamine-restricted diet (0.60 mg/100 g food), both KO and KI mice showed a drastic decrease in blood Thiamine concentrations, dropping to 0.010±0.009 and 0.010±0.006 μM after 5 and 14 days, correspondingly, compared to WT counterparts (0.609±0.288 μM). Additionally, Thiamine levels in the brain homogenates of KO and KI mice were also observed to be lower than in WT mice when fed a conventional diet, with concentrations being 1.33±0.96 nmol/g and 2.16±1.55 nmol/g wet weight, respectively, versus 3.81±2.18 nmol/g in WT. Notably, the Thiamine concentration in brain homogenates of KO and KI mice decreased further to 0.95±0.72 and 1.11±0.24 nmol/g wet weight respectively after 5 and 14 days on a Thiamine-restricted diet, compared to WT mice (3.65±1.02 nmol/g wet weight), ahead of showcasing a disease phenotype. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | DMSO : 4.62 mg/mL (14.1 mM), Sonication is recommended. |
| Keywords | Vitamin B 1 | Vitamin B-1 | Thiamine Nitrate | Inhibitor | Vitamin B1 Nitrate | Thiamine | Endogenous Metabolite | Thiamine nitrate | Vitamin B1 | inhibit |
| Related Compound Libraries | Bioactive Compound Library | Food Additive Library | Natural Product Library | Drug Repurposing Compound Library | Microbial Natural Product Library | Natural Product Library for HTS | FDA-Approved Drug Library | Cosmetic Ingredient Compound Library | Bioactive Compounds Library Max | Gut Microbial Metabolite Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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