Product Details
Product Name:
Terevalefim |
CAS No.:
1070881-42-3 |
Purity:
99.53% |
Supply Ability:
10g |
Release date:
2024/11/19 |
Product Introduction
Bioactivity
Name | Terevalefim |
Description | Terevalefim (ANG-3777) is an hepatocyte growth factor (HGF) mimetic. Terevalefim selectively activates the c-Met receptor. |
In vitro | Terevalefim (ANG-3777) (0-10 μM) significantly inhibited cancer cell proliferation in HUVECs[2]. |
In vivo | Terevalefim (ANG-3777) reduces apoptosis, enhances proliferation, and supports organ repair and function in animal models[1]. Additionally, Terevalefim (ANG-3777, 40 mg/kg, IP) induces phosphorylation of the c-Met receptor in rats[2]. |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Solubility Information | DMSO : 100 mg/mL (567.41 mM), Sonication is recommended.
|
Keywords | ANG-3777 | injury | acute | inhibit | ANG 3777 | AKI | kidney | ANG3777 | Terevalefim | transplantation | c-Met/HGFR | HGF | Inhibitor |
Inhibitors Related | Cabozantinib | Capmatinib 2HCl | SGI-7079 | (±)-Norcantharidin | L-Ascorbic acid 2-phosphate trisodium | Crizotinib | Amuvatinib | Norcantharidin | Cabozantinib S-malate | Capmatinib xHCl | Bacitracin Zinc | Capmatinib |
Related Compound Libraries | Bioactive Compound Library | Membrane Protein-targeted Compound Library | Kinase Inhibitor Library | Tyrosine Kinase Inhibitor Library | Anti-Cancer Clinical Compound Library | Drug Repurposing Compound Library | Clinical Compound Library | Bioactive Compounds Library Max | Anti-Cancer Compound Library | Anti-Cancer Drug Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
You may like
-
CAS:1434643-33-0
$30.00 / 5mg
-
CAS:1307245-86-8
$74.00 / 1mg
-
CAS:634913-39-6
$37.00 / 2mg
Recommended supplier
Product name |
Price |
|
Suppliers |
Update time |
|
$/ |
|
Anhui Ruihan Technology Co., Ltd
|
2023-08-21 |