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Postion:Product Catalog >API>Synthetic Anti-infective Drugs>Antifungal Drugs>Terbinafine Hydrochloride
Terbinafine Hydrochloride
  • Terbinafine Hydrochloride
  • Terbinafine Hydrochloride

Terbinafine Hydrochloride NEW

Price Get Latest Price
Package 1kg
Min. Order: 1kg
Supply Ability: 20tons
Update Time: 2024-04-05

Product Details

Product Name: Terbinafine Hydrochloride CAS No.: 78628-80-5
EC-No.: 616-640-4 Min. Order: 1kg
Purity: 99% Supply Ability: 20tons
Release date: 2024/04/05

Terbinafine hydrochloride is an arylamine with broad-spectrum antifungal activity. It can specifically interfere with the early biosynthesis of fungal ergosterol, highly selective inhibition of fungal squalene epoxidase, so that the squalene epoxidation reaction during the formation of fungal cell membrane is blocked, thus achieving the effect of killing or inhibiting the fungus.
Terbinafine hydrochloride has a fungicidal effect on skin fungi and an inhibitory effect on Candida albicans. It is suitable for skin and nail infections caused by superficial fungi, such as ringworm, ringworm of the body, ringworm of the femur, ringworm of the feet, ringworm of the nail and Candida albicans infection of the skin caused by Trichophyton rubrum, Microsporum canis and Flocculus epidermidis.

 Item Acceptance criteria Result
 Appearance White or almost white powder White powder
 Solubility Freely soluble in anhydrous ethanol and in methanol, slightly   soluble in acetone, very slightly or slightly soluble in water. Conforms
 Identification IR absorption spectrum of sample should be consistent with  spectrum of standard Consistent with spectrum of  standard
 It gives reaction (a) of chlorides using anhydrous ethanol as  solvent Forward reaction
 Related 
substances
  B (Impurity B) W0. 15% N.D
  E (Impurity E) W0. 05% N.D
 (Unspecified impurity) W0. 10% 0.03%
 (Total impurities) W0. 3% 0.09%
 Loss on drying W0. 5% 0.08%
 Sulfated ash W0. 1% 0.04%
 Residual  solvents (Isopropyl alcohol) W5000ppm 94ppm
 (Ethyl acetate) W5000ppm 116ppm
 (Trichloromethane) W60ppm 20ppm
 Assay 99.0%-101.0% (Calculated on the dried basis) 99.70%

Article illustration

Company Profile Introduction

Shaanxi TNJONE Pharmaceutical Co., Ltd supplies more than 2,000 kinds of products, covering the whole field of health industry, including human APIs, veterinary APIs, food additives, natural nutrition ingredients, feed additives, cosmetic additives, intermediates etc. With global sourcing advantages, the group is fully capable of meeting the one-stop sourcing needs of global customers. Today, Shaanxi TNJONE Pharmaceutical Co., Ltd.'s marketing network has spread over more than 100 countries and regions on five continents, providing professional service for global customers.

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Shaanxi TNJONE Pharmaceutical Co., Ltd

1YR ChinaChina
  • Since: 2019-05-23
  • Address: No. 4C-11-A392, Financial Port, Northwest corner of Fengjing Avenue and Fengxin Road, Fengdong New C
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