Tenidap NEW
| Price | $30 | $64 | $109 |
| Package | 1mg | 5mg | 10mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-20 |
Product Details
| Product Name: Tenidap | CAS No.: 120210-48-2 |
| Purity: 99.42% | Supply Ability: 10g |
| Release date: 2024/11/20 |
Product Introduction
Bioactivity
| Name | Tenidap |
| Description | Tenidap (CP-66248) is a selective COX-1 and SLC26A3 inhibitor with anti-inflammatory, analgesic, and anti-rheumatic activities. |
| In vitro | The human astrocytoma cell line U373 MG was incubated with 0.1-100 μM tenidap for 30 min and then stimulated with 50 μM C6-ceramide for 24 h. Tenidap inhibited the dose-dependent ceramide-induced IL-6 protein synthesis in U373 human astrocytoma cells.[4] |
| In vivo | After sustained epilepsy (SE) induced by trichostatin in male Wistar rats, Tenidap was administered at 10 mg / kg daily for 10 days, 46.88 ± 10.70 neurons survived in the tenidap-SE group, and 37.75 ± 8.78 neurons survived in the tenidap-SE group, Tenidap significantly inhibited the hippocampal expression of COX-2 in the hippocampus, especially in the CA3 region.[3] |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | DMSO : 20 mg/mL (62.35 mM), Sonication is recommended. |
| Keywords | Tenidap | CP66248 | CP 66248 |
| Inhibitors Related | 5-Fluorouracil | Bismuth Subsalicylate | Procaine | Ibuprofen | Acetaminophen | Guanidine hydrochloride | Diclofenac sodium | Diclofenac Potassium | N-Nitrosodiethylamine | Thymidine | Paradol | Salicylic acid |
| Related Compound Libraries | Anti-Colorectal Cancer Compound Library | Nonsteroidal Anti-Inflammatory Compound Library | DNA Damage & Repair Compound Library | Pain-Related Compound Library | Bioactive Compound Library | HIF-1 Signaling Pathway Compound Library | Anti-Breast Cancer Compound Library | Inhibitor Library | Anti-Aging Compound Library | Immunology/Inflammation Compound Library | Bioactive Compounds Library Max | Human Metabolite Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36?Washington?Street, Wellesley?Hills
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