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Postion:Product Catalog >TCN 201
TCN 201
  • TCN 201

TCN 201 NEW

Price $59 $98 $182
Package 5mg 10mg 25mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-09

Product Details

Product Name: TCN 201 CAS No.: 852918-02-6
Purity: 98.50% Supply Ability: 10g
Release date: 2024/11/09

Product Introduction

Bioactivity

名稱TCN 201
描述TCN 201 is a selective antagonist of NMDA receptors containing the NR2A subunit.
體外活性TCN-201, a new GluN1/GluN2A-selective NMDA receptor antagonist whose inhibition can be surmounted by glycine.?Electrophysiological recordings from chimeric and mutant rat NMDA receptors suggest that TCN-201 binds to a novel allosteric site located at the dimer interface between the GluN1 and GluN2 agonist binding domains.?Occupancy of this site by TCN-201 inhibits NMDA receptor function by reducing glycine potency.?TCN-201 is therefore a negative allosteric modulator of glycine binding[1].
存儲(chǔ)條件Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
溶解度DMSO : 20 mg/mL (43.3 mM)
關(guān)鍵字GluN1 | Inhibitor | GluN2A | inhibit | TCN201 | iGluR | Ionotropic glutamate receptors | TCN 201 | NMDAR
相關(guān)產(chǎn)品Mephenesin | Decanoic Acid | L-Glutamic acid | glycine | Halothane | L-Glutamic acid monosodium salt | Riluzole | D-Cycloserine | Piracetam | Linalool | O-Phospho-L-serine | Procaine hydrochloride

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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