TC-A 2317 hydrochloride NEW
Price | $3180 |
Package | 50mg |
Min. Order: | |
Supply Ability: | 10g |
Update Time: | 2024-11-19 |
Product Details
Product Name: TC-A 2317 hydrochloride | CAS No.: 1245907-03-2 |
Supply Ability: 10g | Release date: 2024/11/19 |
Product Introduction
Bioactivity
Name | TC-A 2317 hydrochloride |
Description | TC-A 2317 hydrochloride is an inhibitor of Aurora kinase A (Ki of 1.2 nM) and Aurora kinase B (Ki of 101 nM), exhibiting antitumor activity. |
In vivo | In rats, TC-A 2317 hydrochloride (30 mg/kg;p.o.) shows good PK profile; Cmax value is 4930 nM (Tmax=1.2 h) and serum concentration after 24 h is 52 nM (T1/2=3.3 h). In the antitumor mice model, TC-A 2317 hydrochloride is effective without a decrease of body weight[1]. |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Solubility Information | DMSO : <39 mg/mL Ethanol : <19.50 mg/mL |
Keywords | TC-A-2317 Hydrochloride | TC-A 2317 Hydrochloride | permeability | oral | Inhibitor | selective | antitumor | inhibit | HCT-116 | TC A 2317 hydrochloride | TCA 2317 hydrochloride | Aurora Kinase | proliferation | TC-A2317 Hydrochloride | TC-A 2317 |
Inhibitors Related | Palmatine chloride | MK-8745 | SC-514 | Barasertib-HQPA | MBM-55S | SP600125 | KW-2449 | Palmatine | Alisertib | TAK-901 | Tozasertib | TCS7010 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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