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Postion:Product Catalog >TASIN-1 Hydrochloride
TASIN-1 Hydrochloride
  • TASIN-1 Hydrochloride

TASIN-1 Hydrochloride NEW

Price $71 $146 $207
Package 1mg 5mg 10mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-19

Product Details

Product Name: TASIN-1 Hydrochloride CAS No.: 1678515-13-3
Purity: 99.84% Supply Ability: 10g
Release date: 2024/11/19

Product Introduction

Bioactivity

NameTASIN-1 Hydrochloride
DescriptionTASIN-1 Hydrochloride (TASIN-1 HCl) is a selective inhibitor of truncated APC that acts by selectively killing colorectal cancer cells that express truncated APC by reducing cellular cholesterol levels and inducing apoptotic cell death through the ER stress/ROS/JNK signaling in colon cancer cells.
In vivoIn nude mice with established DLD1 and HT29 tumors, intraperitoneal injection of TASIN-1 twice daily for 18 days reduced the size of tumor xenografts and tumor growth rates. TASIN-1 resulted in the appearance of apoptotic cells with fragmented nuclei and induced an increase in cleaved caspase 3 and cleaved PARP1. However, TASIN-1 did not inhibit tumor growth in HCT116 xenografts. In a genetically engineered CRC mouse model, TASIN-1 significantly reduced tumor formation in the colons of CPC [1].
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility InformationDMSO : 55 mg/ml (141.41 mM)
KeywordsTASIN-1 Hydrochloride | TASIN 1 Hydrochloride | TASIN1 Hydrochloride
Inhibitors RelatedTAME | TAME hydrochloride | TASIN-1 | Apcin | Apcin A HCL | CFM 4 | Activated Protein C (390-404), human acetate
Related Compound LibrariesAnti-Colorectal Cancer Compound Library | Bioactive Compound Library | Inhibitor Library | Bioactive Compounds Library Max | Anti-Cancer Compound Library | Anti-Cancer Active Compound Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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