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Postion:Product Catalog >Biochemical Engineering>Biochemical Reagents>Tandospirone citrate
Tandospirone citrate
  • Tandospirone citrate

Tandospirone citrate NEW

Price $48 $77 $156
Package 5mg 10mg 25mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-19

Product Details

Product Name: Tandospirone citrate CAS No.: 112457-95-1
Purity: 99.83% Supply Ability: 10g
Release date: 2024/11/19

Product Introduction

Bioactivity

NameTandospirone citrate
DescriptionTandospirone citrate (SM-3997 citrate) is a potent and selective 5-HT1A receptor partial agonist (Ki : 27 nM)
Cell ResearchIn this double-blind, placebo-controlled, multicenter study, FD patients were randomized to treatment with 10 mg t.i.d. tandospirone citrate or to placebo for 4 weeks. The primary end point was change in abdominal symptom scores. The difference in the proportion of responders (a total abdominal symptom score of 0 or 1) was also assessed. The quality-of-life questionnaire, the SF-8, and a psychological test questionnaire, the State-Trait Anxiety Inventory (STAI), were completed at baseline and at weekly intervals[1]
In vivoImprovements in total abdominal scores were significantly larger with tandospirone than placebo at weeks 1, 2, and 4.?Significantly greater improvements in the tandospirone group were observed in upper abdominal pain (P=0.02) and discomfort (P=0.002) at week 4.?The proportion of responders was significantly greater in the active treatment arm at weeks 3 (P=0.017) and 4 (P=0.0016).?Significant improvements in STAI (P<0.0001) were reported in both arms, as well as in the majority of questions in the SF-8 (P=0.04).?No serious adverse events were reported, with similar rates in both study arms[1]
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility InformationH2O : 10.4 mg/mL (18.07 mM), Sonication is recommended.
DMSO : 50 mg/mL (86.86 mM)
KeywordsSM3997 | Tandospirone Citrate | SM-3997 | Tandospirone | SM3997 Citrate | SM-3997 Citrate | Tandospirone citrate | Inhibitor | SM 3997 Citrate | Serotonin Receptor | SM 3997 | 5-hydroxytryptamine Receptor | inhibit | 5-HT Receptor
Inhibitors RelatedAlverine citrate | Olanzapine | Dapoxetine hydrochloride | CLOZAPINE N-OXIDE | Amitriptyline hydrochloride | Cloperastine hydrochloride | Trazodone hydrochloride | Mianserin hydrochloride | Fluoxetine hydrochloride | Cinchonidine
Related Compound LibrariesAnti-Neurodegenerative Disease Compound Library | Bioactive Compound Library | Pain-Related Compound Library | Membrane Protein-targeted Compound Library | Anti-Cancer Clinical Compound Library | Drug Repurposing Compound Library | Anti-Cancer Approved Drug Library | Bioactive Compounds Library Max | GPCR Compound Library | Anti-Cancer Drug Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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