Talibegron hydrochloride NEW
Price | $49 | $109 | $135 |
Package | 1mg | 5mg | 10mg |
Min. Order: | |
Supply Ability: | 10g |
Update Time: | 2024-11-13 |
Product Details
Product Name: Talibegron hydrochloride | CAS No.: 178600-17-4 |
Purity: 99.82% | Supply Ability: 10g |
Release date: 2024/11/13 |
Product Introduction
Bioactivity
名稱 | Talibegron hydrochloride |
描述 | Talibegron hydrochloride (ZD2079 hydrochloride) is a β3 adrenergic receptor agonist with a pD2 of 3.72 on phenylephrine-preconstricted rat mesenteric artery. It relaxes rat mesenteric artery and isolated aorta in vitro, and inhibits ob gene expression and circulating leptin levels in lean mice in vivo. |
體外活性 | Talibegron hydrochloride ( 0.01-1000 μM) produces a concentration-dependent relaxation of phenylephrine-preconstricted isolated mesenteric arteries and causes full relaxation with 1 mM[1]. |
體內(nèi)活性 | The β3-adrenoceptor agonist talibegron hydrochloride produced a concentration-dependent relaxation of phenylephrine-preconstricted isolated mesenteric arteries. The shape of the concentration–response curve of talibegron hydrochloride also suggests that this drug, which was studied up to 1 mm, causes full relaxation [3]. |
存儲條件 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
溶解度 | H2O : < 8.8 mg/mL DMSO : 50 mg/mL (142.11 mM) |
關(guān)鍵字 | Talibegron Hydrochloride | ZD2079 | ZD2079 Hydrochloride | ZD-2079 Hydrochloride | ZD 2079 Hydrochloride | ZD-2079 |
相關(guān)產(chǎn)品 | Olanzapine | Mirtazapine | Octopamine hydrochloride | Gemfibrozil | Dexmedetomidine hydrochloride | Phenylephrine hydrochloride | Isoprenaline hydrochloride | Amitriptyline hydrochloride | Trazodone hydrochloride | Mianserin hydrochloride |
相關(guān)庫 | 經(jīng)典已知活性庫 | 神經(jīng)信號分子庫 | 膜蛋白靶向化合物庫 | 已知活性化合物庫 | GPCR靶點(diǎn)分子庫 | 抗癌化合物庫 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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