Product Details
Product Name:
SY-640 |
CAS No.:
168705-70-2 |
Purity:
98.82% |
Supply Ability:
10g |
Release date:
2024/11/19 |
Product Introduction
Bioactivity
Name | SY-640 |
Description | SY-640 is an Acetamide derivative. SY-640 exhibits potent hepatoprotective effect. SY-640 reduces liver injury in mice induced by Propionibacterium acnes and Lipopolysaccharide. |
In vitro | SY-640 attenuates the increased expression of leukocyte function-associated antigen-1 and inhibits the number of liver-infiltrating cells[1]. |
In vivo | SY-640, administered orally at a dose of 150 mg/kg once daily for three days, significantly elevates both cytochrome P-450 content and aminopyrine demethylase activity in the liver microsomes of mice. However, hepatic microsomal aminopyrine demethylase activity notably decreases two hours post-administration. Furthermore, a seven-day regimen of the same dose markedly reduces liver injury induced by Propionibacterium acnes and Lipopolysaccharide, whereas a single dose proves ineffective. |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Solubility Information | DMSO : 95 mg/mL (458.43 mM)
|
Keywords | Acetamide | inhibit | acnes | Propionibacterium | Endogenous Metabolite | hepatoprotective | Lipopolysaccharide | SY-640 | Inhibitor | SY 640 | SY640 |
Inhibitors Related | Sucrose | Daidzein | Guanidine hydrochloride | Fumaric acid | Ferulic Acid | Geraniol | Formamide | Oleamide | Glycerol | Thymidine | Naringin | Oxalic acid dihydrate |
Related Compound Libraries | Bioactive Compound Library | Orally Active Compound Library | Bioactive Compounds Library Max |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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Price |
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Suppliers |
Update time |
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$99.00/1EA |
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2018-10-12 |