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Postion:Product Catalog >SW2_110A
SW2_110A
  • SW2_110A

SW2_110A NEW

Price $110 $289 $788
Package 1mg 5mg 25mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-19

Product Details

Product Name: SW2_110A CAS No.: 2579696-95-8
Purity: 98% Supply Ability: 10g
Release date: 2024/11/19

Product Introduction

Bioactivity

NameSW2_110A
DescriptionSW2_110A is a cell-permeable, selective chromosome group 8 chromosome domain (CBX8 ChD) inhibitor with a Kd of 800 nM. In vitro, SW2_110A is 5-fold more selective for CBX8 ChD than all other CBX enantiomers.
In vitroSW2_110A (100 μM; 24h) explicitly inhibits the association of CBX8 with chromatin in cells and inhibits the proliferation of THP1 leukemia cells driven by the MLL-AF9 translocation (IC50 of 26 μM). In THP1 cells, SW2_110A (100 μM; 24h) treatment results in a significant decrease in the expression of MLL-AF9 target genes, including HOXA9.[1]
Storagestore at low temperature,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility InformationDMSO : 112.5 mg/mL (147.8 mM), Sonication is recommended.
KeywordsSW-2_110A | SW2_110A
Inhibitors RelatedBIX-01294 trihydrochloride | Tazemetostat | Piribedil | XY1 | UNC 0631 | GSK126 | MAK683 | EZM 2302 | EPZ015666 | AMI-1 free acid | MS37452 | MRTX-1719
Related Compound LibrariesHistone Modification Compound Library | Bioactive Compound Library | Inhibitor Library | Bioactive Compounds Library Max

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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