Sulfadoxine
Price | Get Latest Price | ||
Package | 1kg | 5kg | 10kg |
Min. Order: | 1kg |
Supply Ability: | 1000 |
Update Time: | 2024-12-26 |
Product Details
Product Name: Sulfadoxine | CAS No.: 2447-57-6 |
Min. Order: 1kg | Purity: 98 |
Supply Ability: 1000 | Release date: 2024/12/26 |
Product Name: Sulfadoxine
Synonyms: 4-amino-n-(5,6-dimethoxy-4-pyrimidinyl)-benzenesulfonamid;6-(4-aminobenzenesulfonamido)-4,5-dimethoxypyrimidine;fanasil;sulforthomidine;6-(4-aminobenzenesulfonamide)-4,5-dimethoxypyrimidine;4-sulfanilamido-5,6-dimethoxypyrimidine;4-AMINO-N-(5,6-DIMETHOXY-4-PYRIMIDINYL)BENZENESULFONAMIDE;Sulfadoxine BP2000/USP25
CAS: 2447-57-6
MF: C12H14N4O4S
MW: 310.33
EINECS: 219-504-9
Product Categories: API;FANASIL;Intermediates & Fine Chemicals;Pharmaceuticals;Antibiotics;Pharmaceutical intermediate;Miscellaneous Natural Products;BacteriostaticAntibiotics;Chemical Structure;OthersAlphabetic;Principle;S;SN - SZ;Amines;Aromatics;Sulfur & Selenium Compounds
Sulfadoxin is a sulfonamide antibiotic that inhibits dihydropteroate synthetase (DHPS), an enzyme involved in folic acid synthesis. Sulfadoxin competes with 4-aminobenzoate (PABA), the native substrate of DHPS, and inhibits PABA incorporation into folic acid. Folate is essential for purine and pyrimidine synthesis, therefore, sulfadoxin has antiproliferative activity in non-resistant P. falciparum. Sulfadoxin inhibits growth of P. falciparum in vitro, but potency varies between non-resistant (IC50 = 4 ng/ml) and resistant strains (IC50 = 3,970 ng/ml).
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- Since: 2024-03-12
- Address: Room 02-31, 13 / F, Building 9, Guannan Fuxing Medical Park Phase II, No.58, Guanggu Avenue, East La